12 documents found, page 1 of 2
Psychometric properties of the hypoglycemia fear survey—Parents (HFS-P) in the ...
Costa, Vasco; Patton, Susana R.; Vale, Sónia do; Sampaio, Lurdes; Limbert, Catarina; Brandão, TâniaBackground/Objectives: Hypoglycemia occurs when blood glucose levels drop significantly below the normal range leading to unpleasant symptoms and a greater risk of acute complications. Fear of hypoglycemia (FH) is a conditioned psychological response to hypoglycemia frequently experienced by people with type 1 diabetes (T1D) and their loved ones. The present study aimed to examine the psychometric properties of...
Connective tissue disease as a cause of discrepant capillary and serum glucose ...
Matos, Tânia; Rocha, José Vicente; Barreira, Sofia; Vale, Sónia do; Bugalho, Maria JoãoCapillary glucose measurement is widely used for point-of-care testing and for self-monitoring of blood glucose. Nevertheless, fingertip capillary glucose assessment has some limitations and could lead to erroneous estimations in several situations, such as problems associated with certain medications or conditions related to hyperviscosity or to impaired capillary blood flow.
Type la glycogen storage disease complicated with diabetes mellitus: the role o...
Marcalo, Jose; Oliveira, Anabela; Nunes, Patricia Almeida; Vale, Sónia doA 22-year-old woman with type Ia glycogen storage disease was referred to the endocrinology department with new-onset diabetes mellitus-glycated haemoglobin (HbA1c) of 8.2%. She had suffered from repeated bouts of hypoglycaemia since the first days of her life. The diagnosis was made at 5 months old, after clinical investigations revealed mixed dyslipidaemia, lactic acidosis and hepatomegaly. Compound heterozyg...
Retinal vascular reactivity in type 1 diabetes patients without retinopathy usi...
Sousa, David Cordeiro; Leal, Ines; Moreira, Susana; Vale, Sónia do; Silva-Herdade, Ana S.; Aguiar, Patrício; Dionísio, Patrícia; Pinto, LuisPurpose: We hypothesize that patients with type 1 diabetes (T1D) may have abnormal retinal vascular responses before diabetic retinopathy (DR) is clinically evident. Optical coherence tomography angiography (OCTA) was used to dynamically assess the retinal microvasculature of diabetic patients with no clinically visible retinopathy. Methods: Controlled nonrandomized interventional study. The studied population ...
Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interact...
Figueiredo, Joana; Serrado, Margarida; Khmelinskii, Nikita; Vale, Sónia doInhaled corticosteroids are generally considered safe and do not usually lead to systemic adverse events since their plasma concentrations are low due to hepatic metabolism by the cytochrome P450 3A4. However, when associated with inhibitors of this cytochrome, such as ritonavir, they may lead to iatrogenic Cushing syndrome by the systemic accumulation of corticosteroids and consequent suppression of the hypoth...
Optical coherence tomography angiography study of the retinal vascular plexuses...
Sousa, David Cordeiro; Leal, Ines; Moreira, Susana; Vale, Sónia do; Silva-Herdade, Ana S.; Dionísio, Patrícia; Castanho, Miguel A. R. B.; Pinto, LuisAim Previous data suggest the existence of retinal vascular changes and impaired autoregulation in the very early stages of diabetic retinopathy (DR). We compared the retinal plexuses between patients with type 1 diabetes (T1D) without DR and a demographically similar healthy cohort, using optical coherence tomography angiography (OCT-A). Methods Patients with T1D and no signs of DR were prospectively recruited...
A protocol to evaluate retinal vascular response using optical coherence tomogr...
Sousa, David Cordeiro; Leal, Ines; Moreira, Susana; Vale, Sónia do; Silva-Herdade, Ana S.; Aguiar, Patrício; Dionísio, Patrícia; Pinto, LuisIntroduction: Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and vasoconstriction retinal vascular responses with the available OCT-A technology. Methods: A co...
Methimazole associated eosinophilic pleural effusion: a case report
Gaspar da Costa, Pedro; Duarte Silva, Filipa; Henriques, Júlia; Vale, Sónia do; Braz, Sandra; Meneses Santos, João; M.M. Victorino, RuiBackground: Adverse reactions associated to anti-thyroid drugs include fever, rash, arthralgia, agranulocytosis and hepatitis that are thought to be hypersensitivity reactions. Five cases of pleural effusion associated to thionamides have also been reported, two with propylthiouracil and three with carbimazole. Case presentation: We report here a case of a 75-year-old man admitted because of unilateral pleural ...
Takotsubo syndrome : a pathway through the pituitary disease
Plácido, Rui; Martins, Ana Filipa; Martins, Susana Robalo; Vale, Sónia do; Almeida, Ana G.; Pinto, Fausto J.; Martins, João MartinTakotsubo cardiomyopathy (TTC) is characterized by reversible left ventricular apical and/or midventricular hypokinesia with unknown etiology. The clinical presentation is similar to acute myocardial infarction in the absence of significant obstructive coronary artery disease. Various predisposing factors have been related to TTC, such as acute neurological illnesses, endocrine diseases, pain, and emotional str...
Mild adrenal steroidogenic defects and ACTH-dependent aldosterone secretion in ...
Martins, João Martin; Vale, Sónia do; Martins, Ana FilipaIntroduction. Adrenal glands play a major role in the control of blood pressure and mild defects of steroidogenesis and/or inappropriate control of mineralocorticoid production have been reported in high blood pressure (HBP). Patients and Methods. We used a specific protocol for the evaluation of 100 consecutive patients with inappropriate or recent onset HBP. Specific methods were used to confirm HBP and to di...