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Cumulus cell DNA damage linked to fertilization success in females with an ovul...

Rodrigues, B; Sousa, V; Esteves, F; Vale-Fernandes, E; Costa, S; Sousa, D; Brandão, R; Leal, C; Pires, J; Gaivão, I; Teixeira, JP; Nogueira, AJA

Intracytoplasmic sperm injection (ICSI) is a widely used technique in fertility centers. ICSI success depends on both nuclear and cytoplasmic oocyte maturation. Cumulus cells, which surround the oocytes, play a pivotal role in oocyte competence. However, the significance of DNA damage in cumulus cells as a marker of fertilization success remains largely unexplored. This study aims to investigate the relationshi...


Payment to gamete donors: equality, gender equity, or solidarity?

Samorinha, C; de Freitas, C; Baía, I; Machado, H; Vale-Fernandes, E; Silva, S

Purpose: Regulation of payment to gamete donors varies substantially across countries. The development of an ethically sustainable governance system of payments in gamete donation demands that the preferences of different stakeholders be heard. This study intends to contribute to improving the understanding of payment to gamete donors by analysing the views of donors and recipients about the preferred form of p...


Single Fetal Death in Monochorionic Twin Pregnancy: Co-Twin Prognosis and Neona...

Vale-Fernandes, E; Dias, J; Gil, B; Cadilhe, A

The incidence of single fetal death in twin pregnancy varies from 0.5% - 6.8%, leaving the surviving fetus with increased morbi-mortality. The prognosis is worse in monochorionic pregnancies. In addressing these cases it should be noted referral to tertiary center with differentiated perinatal support, induction of fetal lung maturation and termination of pregnancy if there's loss of fetal well-being or possibi...


Assisted Reproductive Technology in Female Transplant Recipients: Experience of...

Vale-Fernandes, E; Póvoa, AM; Soares, S; Calejo, L; Xavier, P; Sousa, S; Beires, J; Montenegro, N

Diseases in end stage typically occur with hypothalamic-pituitary-ovarian axis disorders, with consequent anovulation and infertility. The solid organ transplantation increased survival of patients with end-stage organs disease and the vast majority of women improve their reproductive capacity after transplantation. Although adoption can always be a possibility, the transplanted infertile woman has the right to...


Uterine Rupture at 18 Weeks of Pregnancy in the Context of Malformed Uterus

Vale-Fernandes, E; Teixeira, N; Cadilhe, A; Rocha, MJ

Birth defects of the female genital tract are relatively common and often asymptomatic. Despite the pregnancy outcome can be favorable, adverse obstetric outcomes are described in women with uterine malformations. The authors report the case of an obstetric emergency which enhances the possibility of a very adverse and rare outcome of uterine rupture in a left hemi-cavity of a bicornuate uterus away from the te...


Assisted Reproductive Technology in Female Transplant Recipients: Experience of...

Vale-Fernandes, E; Póvoa, AM; Soares, S; Calejo, L; Xavier, P; Sousa, S; Beires, J; Montenegro, N

Diseases in end stage typically occur with hypothalamic-pituitary-ovarian axis disorders, with consequent anovulation and infertility. The solid organ transplantation increased survival of patients with end-stage organs disease and the vast majority of women improve their reproductive capacity after transplantation. Although adoption can always be a possibility, the transplanted infertile woman has the right to...






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