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Potential of omega-3 and conjugated fatty acids to control microglia inflammato...

Salsinha, A. S.; Socodato, R.; Rodrigues, A.; Vale-Silva, R.; Relvas, J. B.; Pintado, M.; Rodríguez-Alcalá, L. M.

High-fat diet-induced obesity detrimentally affects brain function by inducing chronic low-grade inflammation. This neuroinflammation is, at least in part, likely to be mediated by microglia, which are the main immune cell population in the brain. Microglia express a wide range of lipid-sensitive receptors and their activity can be modulated by fatty acids that cross the blood-brain barrier. Here, by combining ...

Date: 2023   |   Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa
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