4 documents found, page 1 of 1
A whole genome screen for association with multiple sclerosis in Portuguese pat...
Santos, M; Pinto-Basto, J; Rio, ME; Sá, MJ; Valença, A; Sá, A; Dinis, J; Figueiredo, J; Bigotte de Almeida, L; Coelho, I; Sawcer, S; Setakis, EMultiple sclerosis (MS) is common in Europe affecting up to 1:500 people. In an effort to identify genes influencing susceptibility to the disease, we have performed a population-based whole genome screen for association. In this study, 6000 microsatellite markers were typed in separately pooled DNA samples from MS patients (n=188) and matched controls (n=188). Interpretable data was obtained from 4661 of these...
Nursing education in a new model of health care.
Valença, A; Braguêz, LThe health care attitude has been changing over the last years. From just comforting the patient and treating the illness, the winds are blowing toward prevention and, more recently, to promote health as a goal. The changing philosophy must have consequences in Education of Health professionals, namely in Nursing. The authors made an inquiry to third year nurse students of a school in Lisbon, asking them to rat...
A case of Wilson's disease studied using magnetic resonance: a new approach?.
Valença, A; Goulão, A; Leitão, O; Veloso, M; Breia, A P; Guimarães, J; Evangelista, P; Maurício, J CWilson's disease is a genetically determined disorder of copper metabolism with increased deposition in brain and liver. With current imaging techniques--CT scan and conventional Nuclear Magnetic Resonance (NMR)--it has been possible to demonstrate oedema, neuronal loss and reactive gliosis, but not copper deposition. In the present study we report the observations, done in one patient, using a new high magneti...
Meningeal carcinomatosis. A one year's case load; review of the literature.
Valença, A; Marques, J M10 cases of meningeal carcinomatosis treated in the Neurological Unit at the Instituto Português de Oncologia de Francisco Gentil in Lisbon are presented. Pertinent bibliography is reviewed, particularly the one concerned with physiopathology and treatment. Some research topics about biological response modifiers and drug transport systems are mentioned.; 10 cases of meningeal carcinomatosis treated in the Neur...