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Prostate cancer proliferation is affected by the subcellular localization of MC...

Valença, I; Ferreira, AR; Correia, M; Kühl, S; Roermund, C; Waterham, HR; Máximo, V; Islinger, M; Ribeiro, D

Reprogramming of lipid metabolism directly contributes to malignant transformation and progression. The increased uptake of circulating lipids, the transfer of fatty acids from stromal adipocytes to cancer cells, the de novo fatty acid synthesis, and the fatty acid oxidation support the central role of lipids in many cancers, including prostate cancer (PCa). Fatty acid ß-oxidation is the dominant bioenergetic p...

Date: 2020   |   Origin: Repositório Aberto da Universidade do Porto
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