Made available in DSpace on 2022-04-28T19:48:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Gene regulatory networks (GRNs) play key roles in development, phenotype plasticity, and evolution. Although graph theory has been used to explore GRNs, associations amongst topological features, transcription factors (TFs), and systems esse...
Made available in DSpace on 2022-04-29T09:12:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-12-01; Decades before the recent advances in molecular biology and the knowledge of the complete nucleotide sequence of several genomes, cytogenetic analysis provided the first information concerning the genome organization. The exploration of molecular biology techniques in the cytogenetic area represents a p...
Made available in DSpace on 2021-06-25T10:11:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Hepatitis B virus (HBV) is an enveloped virus that induces chronic liver disease. HBV has been classified into eight genotypes (A–H) according to its genome sequence by using Sanger sequencing or reverse hybridization. Sanger sequencing is o...
Made available in DSpace on 2021-06-25T10:17:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; The lack of consensus concerning the biological meaning of entropy and complexity of genomes and the different ways to assess these data hamper conclusions concerning what are the causes of genomic entropy variation among species. This study aims to evaluate the entropy and complexity of genomic sequenc...
Made available in DSpace on 2020-12-10T19:40:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Fundacao Araucaria (Fundacao Araucaria de Apoio ao Desenvolvimento Cientifico e Tecnologico do Estado do Parana); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológ...
Made available in DSpace on 2020-12-12T01:36:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Most of the bioinformatics tools for enzyme annotation focus on enzymatic function assignments. Sequence similarity to well-characterized enzymes is often used for functional annotation and to assign metabolic pathways. However, these approaches are not feasible for all sequences leading to inaccurate a...
Made available in DSpace on 2020-12-12T01:55:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Leishmaniasis is caused by intracellular parasites transmitted to vertebrates by sandfly bites. Clinical manifestations include cutaneous, mucosal or visceral involvement d...
Made available in DSpace on 2020-12-12T01:57:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Key message: A survey of theEucalyptus grandis genome revealed the presence of 54 laccase genes. Their...
Made available in DSpace on 2019-10-06T16:52:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The fermentation process is widely used in the industry for bioethanol production. Even though it is widely used, microbial contamination is unpredictable and difficult to control. The problem of reduced productivity is directly linke...
Made available in DSpace on 2019-10-06T16:11:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-15; Universidade Estadual Paulista; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Mass spectrometry is the most used method for protein identification and quantification. Here we developed four protein extraction protocols precisely for mass spectrometry, and we compared with other ones alr...