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Carcinoid Complexity: A Syndrome Revealing Lung Tumor and Heart Disease

R. Lopes, Sofia; Barata, Juliana; Marques Vicente Lopes, Maria Inês; Valente, Salete

N/A; N/A

Date: 2025   |   Origin: Acta Médica Portuguesa

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-S...

Alexandre, Daniela; Polido, Joana; Valente, Salete; Rocha, Daniel Pimenta; Fernandes, Alexandra R.; Baptista, Pedro V.; Cruz, Carla

Background/Objectives: Late diagnosis hampers effective treatment of non-small cell lung cancer (NSCLC). This study evaluated whether circulating microRNAs (miRs), miR-155 and miR-3196, measured in liquid biopsy peripheral blood mononuclear cells (PBMCs), can serve as potential non-invasive biomarkers for NSCLC diagnosis, patient stratification, therapy monitoring, and prognosis. Methods: RNA was isolated from ...


Atypical Esophageal Metastasis in the Thoracic Wall

R. Lopes, Sofia; Baptista, Mafalda; Gonçalves, Carla; Vicente, Inês; Valente, Salete

N/a.; N/a.

Date: 2024   |   Origin: Acta Médica Portuguesa

Two-year treatment with Pembrolizumab monotherapy in advanced non-small cell lu...

Costa-Martins, Sara; Valente, Salete; Pêgo, Alice; Figueiredo, Ana; Barata, Fernando

Introduction and objectives: Immunotherapy has introduced advances in the treatment of non -small cell lung cancer. However, data from current clinical practice on potential responder groups, optimal duration of treatment and safety issues remain unclear. It is intended to produce a reflection on the population of patients with a favourable response to Pembrolizumab and how they have evolved clinically over tim...


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