2 documents found, page 1 of 1
Control of tissue growth by Yap relies on cell density and F-actin in zebrafish...
Mateus, Rita; Lourenço, Raquel; Fang, Y.; Brito, G; Farinho, Ana; Valerio, Fabio; Jacinto, AntonioThis work was supported by funding from Fundacao para a Ciencia e Tecnologia [SFRH/BD/62126/2009, PTDC/BEX-BID/1176/2012]; and Agence Nationale de la Recherche [ANR-11-BSV5-0021].; Caudal fin regeneration is characterized by a proliferation boost in the mesenchymal blastema that is controlled precisely in time and space. This allows a gradual and robust restoration of original fin size. However, how this is est...
A new zebrafish bone crush injury model
Sousa, Sara; Valerio, Fabio; Jacinto, AntonioWhile mammals have a limited capacity to repair bone fractures, zebrafish can completely regenerate amputated bony fin rays. Fin regeneration in teleosts has been studied after partial amputation of the caudal fin, which is not ideal to model human bone fractures because it involves substantial tissue removal, rather than local tissue injury. In this work, we have established a bone crush injury model in zebraf...