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The Demise of Multidrug-Resistant HIV-1: the National Time Trend in Portugal

Vercauteren, J; Theys, K; Carvalho, AP; Valadas, E; Duque, LM; Teófilo, E; Faria, T; Faria, D; Vera, J; Aguas, MJ; Peres, S; Mansinho, K; Vandamme, AM

OBJECTIVES: Despite a decreasing mortality and morbidity in treated HIV-1 patients, highly active antiretroviral treatment (HAART) can still fail due to the development of drug resistance. Especially, multidrug-resistant viruses pose a threat to efficient therapy. We studied the changing prevalence of multidrug resistance (MDR) over time in a cohort of HIV-1-infected patients in Portugal. PATIENTS AND METHODS: ...

Date: 2013   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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Different substitutions under drug pressure at protease codon 82 in HIV-1 subty...

Camacho, R; Godinho, AR; Gomes, P; Abecasis, A; Vandamme, AM; Palma, C; Carvalho, AP; Cabanas, J; Goncalves, J

Date: 2005   |   Origin: Repositório da Universidade de Lisboa
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