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One-carbon metabolism and global DNA methylation in mothers of individuals with...

Mendes, Cristiani Cortez; Zampieri, Bruna Lancia; Arantes, Lidia Maria Rebolho Batista; Melendez, Matias Eliseo; Biselli, Joice Matos [UNESP]

Made available in DSpace on 2022-04-29T08:32:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Down syndrome (DS) is the most common chromosomal disorder, resulting from the failure of normal chromosome 21 segregation. Studies have suggested that impairments within the one-carbon metabolic pathway can be of relevance for the global genome instability observed in mothers of individuals with DS. Ba...

Date: 2022   |   Origin: Oasisbr










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