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Characterization of Genetic Polymorphisms CYP2R1 rs2060793 and CYP2R1 rs1279471...

Varandas, Tatiana; Dias, Francisca; Sousa, Ana; Sousa, Maria; Medeiros, Rui

Background: Endometriosis is an estrogen-dependent gynecologic disorder defined by the presence of endometrium outside the uterine cavity [1, 2]. Vitamin D is a steroid hormone known for its importance in various biological processes [3]. Vitamin D may play a direct role in the changes that the endometrium undergoes during the menstrual cycle, as endometrial tissue also expresses enzymes involved in metabolism ...


Impact of cervicovaginal microbiome on the risk of cervical abnormalities devel...

Rosário, Andreia; Sousa, Ana Isabel; Varandas, Tatiana; Marinho-Dias, Joana; Medeiros, Rui; Martins, Maria Gabriela; Monteiro, Paula; Sousa, Hugo

The vaginal microbiome has emerged as potentially influencing the natural history of Human Papillomavirus (HPV) infections and their clinical impact. We aimed to characterize the vaginal microbiome in samples from 807 high-risk HPVs (Hr-HPV) positive women with a mean age of 41.45 +/- 10.79 years who participated in the Regional Cervical Cancer Screening Program from the Northern Region of Portugal. Microbiome ...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Characterization of genetic polymorphisms CYP2R1 rs2060793 and CYP2R1 rs1279471...

Varandas, Tatiana; Dias, Francisca; Sousa, Ana; Amorim, Manuela; Medeiros, Rui

Endometriosis is an estrogen-dependent gynecologic disorder defined by the presence of endometrium outside the uterine cavity. Vitamin D is a steroid hormone known for its importance in various biological processes. Vitamin D may play a direct role in the changes that the endometrium undergoes during the menstrual cycle, as endometrial tissue also expresses enzymes involved in metabolism. The study of genetic p...


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