16 documents found, page 1 of 2
Targeting Skin Aging Hallmarks In Vitro: Antioxidant, Anti-Inflammatory, and An...
Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Costa, Ricardo M. F. da; Marques, Joana; Carvalho, Luís A. E. Batista de; Silva, AnaPlant-based extracts are rich sources of phenolic compounds, which may act as skin antiaging mediators. Herein, Cistus albidus L. (Ca), Cistus ladanifer L. subsp. ladanifer (Cl) and Cistus salviifolius L. (Cs) were selected to test whether their phytochemical profile and bioactive potential align to target human skin aging. Hydroethanolic extracts (HEs) were prepared and characterized using infrared vibrational...
A Spectrochemically Driven Study: Identifying Phenolic-Rich Extracts from Helic...
Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Costa, Ricardo M. F. da; Marques, Joana; Carvalho, Luís A. E. Batista de; Silva, AnaPlants inhabiting mediterranean-influenced climatic zones, like Helichrysum stoechas (L.) Moench subsp. stoechas, Lavandula pedunculata (Mill.) Cav., and Thymus mastichina (L.) L. subsp. mastichina, have been scarcely investigated regarding their richness in phenolic compounds, herein explored as sources of skin anti-aging compounds. In this investigation, Fourier transform infrared spectroscopy (FTIR) in atten...
Chemical Characterization and Differential Lipid-Modulating Effects of Selected...
Amorim, Ricardo; Marques, Mário Pedro; Melim, Catarina; Varela, Carla; Sardão, Vilma A.; Teixeira, José; Dias, Maria Inês; Barros, LillianCôa Valley, located in the northeast of Portugal, harbors more than 500 medicinal plant species. Among them, four species stand out due to their traditional uses: Equisetum ramosissimum Desf. (hemorrhages, urethritis, hepatitis), Rumex scutatus L. subsp. induratus (Boiss. and Reut.) Malag. (inflammation, constipation), Geranium purpureum Vill., and Geranium lucidum L. (pain relief, gastric issues). Given their ...
Optimizing lignin cationization: unveiling the impact of reaction conditions th...
Fernandes, Catarina; Gomes, Leandro Cid; Bernin, Diana; Alves, Luís; Rasteiro, Maria Graça; Medronho, Bruno; Varela, CarlaLignin, a natural and abundant biopolymer, holds great potential for cosmetic applications. However, its limited solubility and inherently negative charge restrict its use in certain formulations. This is particularly relevant for hair conditioning, where a positively charged polymer is preferred to effectively treat negatively charged damaged hair. To overcome this limitation, lignin extracted from acacia wood...
Lignin extraction from acacia wood: crafting deep eutectic solvents with a syst...
Fernandes, Catarina; Aliaño González, María José; Gomes, Leandro Cid; Bernin, Diana; Gaspar, Rita; Fardim, Pedro; Reis, Marco S.; Alves, LuísLignin is a complex biopolymer whose efficient extraction from biomass is crucial for various applications. Deep eutectic solvents (DES), particularly natural-origin DES (NADES), have emerged as promising systems for lignin fractionation and separation from other biomass components. While ternary DES offer enhanced fractionation performance, the role of each component in these mixtures remains unclear. In this ...
An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromat...
Amaral, Cristina; Correia-da-Silva, Georgina; Almeida, Cristina Ferreira; Valente, Maria João; Varela, Carla; Tavares-da-Silva, ElisiarioAround 70-85% of all breast cancer (BC) cases are estrogen receptor-positive (ER+). The third generation of aromatase inhibitors (AIs) is the first-line treatment option for these tumors. Despite their therapeutic success, they induce several side effects and resistance, which limits their efficacy. Thus, it is crucial to search for novel, safe and more effective anti-cancer molecules. Currently, multi-target d...
Inteligência emocional, resiliência e stress nos/as interventores/as sociais
Gameiro, Fátima; Ribeiro, Catarina; Bento, Bianca; Coutinho, Catarina; Pereira, Mariana; Silva, Micaela; Santana, Thiessa; Varela, Carla; Raio, AnaOs seres humanos sempre enfrentaram vários obstáculos ao longo de várias gerações, todavia nestes últimos quatro anos viram-se frente a frente com a pandemia COVID-19 e respetivos confinamentos, a hipótese de uma 3ª GM, mudanças climáticas, desastres naturais, subida da inflação e muitas outras dificuldades. Este estudo tem como objetivo avaliar a perceção da inteligência emocional (IE), resiliência (Rs) e stre...
Inteligência emocional, resiliência e stress nos/as interventores/as sociais
Gameiro, Fátima; Ribeiro, Catarina; Bento, Bianca; Coutinho, Catarina; Pereira, Mariana; Silva, Micaela; Santana, Thiessa; Varela, Carla; Raio, AnaOs seres humanos sempre enfrentaram vários obstáculos ao longo de várias gerações, todavia nestes últimos quatro anos viram-se frente a frente com a pandemia COVID-19 e respetivos confinamentos, a hipótese de uma 3ª GM, mudanças climáticas, desastres naturais, subida da inflação e muitas outras dificuldades. Este estudo tem como objetivo avaliar a perceção da inteligência emocional (IE), resiliência (Rs) e stre...
Essential oils from coa valley lamiaceae species: cytotoxicity and antiprolifer...
Marques, Mário Pedro; Neves, Beatriz Guapo; Varela, Carla; Zuzarte, Mónica; Goncalves, Ana Cristina; Dias, Maria Inês; Amaral, Joana S.; Barros, LillianLavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L.) L. subsp. mastichina are representative species of the Coa Valley's flora, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are traditionally used to preserve olives and to aromatize bonfires on Saint John's Eve, while M. cervina is mainly used as a spice for river fish dishes. Despite their traditional use...
Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and ...
Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo; Carvalho, Luís de; Carvalho, Aida; Oliveira, Paulo; Cabral, CéliaCôa Valley is a Northeast region of Portugal, classified as a UNESCO World Her- itage Site since 1998, and recognised as “the most important open-air Paleo- lithic rock art site”. So far, little is known about the natural endogenous resourc- es of this territory, namely medicinal plants. According to a preliminary ethnobotanical survey in this region, several medicinal plants were mentioned to have skin-benefic...