14 documents found, page 1 of 2
Chemical Characterization and Differential Lipid-Modulating Effects of Selected...
Amorim, Ricardo; Marques, Mário Pedro; Melim, Catarina; Varela, Carla; Sardão, Vilma A.; Teixeira, José; Dias, Maria Inês; Barros, LillianCôa Valley, located in the northeast of Portugal, harbors more than 500 medicinal plant species. Among them, four species stand out due to their traditional uses: Equisetum ramosissimum Desf. (hemorrhages, urethritis, hepatitis), Rumex scutatus L. subsp. induratus (Boiss. and Reut.) Malag. (inflammation, constipation), Geranium purpureum Vill., and Geranium lucidum L. (pain relief, gastric issues). Given their ...
Optimizing lignin cationization: unveiling the impact of reaction conditions th...
Fernandes, Catarina; Gomes, Leandro Cid; Bernin, Diana; Alves, Luís; Rasteiro, Maria Graça; Medronho, Bruno; Varela, CarlaLignin, a natural and abundant biopolymer, holds great potential for cosmetic applications. However, its limited solubility and inherently negative charge restrict its use in certain formulations. This is particularly relevant for hair conditioning, where a positively charged polymer is preferred to effectively treat negatively charged damaged hair. To overcome this limitation, lignin extracted from acacia wood...
Lignin extraction from acacia wood: crafting deep eutectic solvents with a syst...
Fernandes, Catarina; Aliaño González, María José; Gomes, Leandro Cid; Bernin, Diana; Gaspar, Rita; Fardim, Pedro; Reis, Marco S.; Alves, LuísLignin is a complex biopolymer whose efficient extraction from biomass is crucial for various applications. Deep eutectic solvents (DES), particularly natural-origin DES (NADES), have emerged as promising systems for lignin fractionation and separation from other biomass components. While ternary DES offer enhanced fractionation performance, the role of each component in these mixtures remains unclear. In this ...
An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromat...
Amaral, Cristina; Correia-da-Silva, Georgina; Almeida, Cristina Ferreira; Valente, Maria João; Varela, Carla; Tavares-da-Silva, ElisiarioAround 70-85% of all breast cancer (BC) cases are estrogen receptor-positive (ER+). The third generation of aromatase inhibitors (AIs) is the first-line treatment option for these tumors. Despite their therapeutic success, they induce several side effects and resistance, which limits their efficacy. Thus, it is crucial to search for novel, safe and more effective anti-cancer molecules. Currently, multi-target d...
Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and ...
Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo; Carvalho, Luís de; Carvalho, Aida; Oliveira, Paulo; Cabral, CéliaCôa Valley is a Northeast region of Portugal, classified as a UNESCO World Her- itage Site since 1998, and recognised as “the most important open-air Paleo- lithic rock art site”. So far, little is known about the natural endogenous resourc- es of this territory, namely medicinal plants. According to a preliminary ethnobotanical survey in this region, several medicinal plants were mentioned to have skin-benefic...
Essential oils from coa valley lamiaceae species: cytotoxicity and antiprolifer...
Marques, Mário Pedro; Neves, Beatriz Guapo; Varela, Carla; Zuzarte, Mónica; Goncalves, Ana Cristina; Dias, Maria Inês; Amaral, Joana S.; Barros, LillianLavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L.) L. subsp. mastichina are representative species of the Coa Valley's flora, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are traditionally used to preserve olives and to aromatize bonfires on Saint John's Eve, while M. cervina is mainly used as a spice for river fish dishes. Despite their traditional use...
Inteligência emocional, resiliência e stress nos/as interventores/as sociais
Gameiro, Fátima; Ribeiro, Catarina; Bento, Bianca; Coutinho, Catarina; Pereira, Mariana; Silva, Micaela; Santana, Thiessa; Varela, Carla; Raio, AnaOs seres humanos sempre enfrentaram vários obstáculos ao longo de várias gerações, todavia nestes últimos quatro anos viram-se frente a frente com a pandemia COVID-19 e respetivos confinamentos, a hipótese de uma 3ª GM, mudanças climáticas, desastres naturais, subida da inflação e muitas outras dificuldades. Este estudo tem como objetivo avaliar a perceção da inteligência emocional (IE), resiliência (Rs) e stre...
Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and ...
Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo M.F. da; Carvalho, Luís A.E. Batista de; Carvalho, AidaWhere is located and what is the importance of river Côa Valley? • The river Côa Valley is part of the Guarda District, in the Northeast of Portugal. The Valley comprises an Archeological Park, which is considered “the most important open-air Paleolithic rock art site” in the world, being classified as UNESCO World Heritage Site since 1998. What are the natural resources’ relevance of this region? • The flora o...
Inteligência emocional, resiliência e stress nos/as interventores/as sociais
Gameiro, Fátima; Ribeiro, Catarina; Bento, Bianca; Coutinho, Catarina; Pereira, Mariana; Silva, Micaela; Santana, Thiessa; Varela, Carla; Raio, AnaOs seres humanos sempre enfrentaram vários obstáculos ao longo de várias gerações, todavia nestes últimos quatro anos viram-se frente a frente com a pandemia COVID-19 e respetivos confinamentos, a hipótese de uma 3ª GM, mudanças climáticas, desastres naturais, subida da inflação e muitas outras dificuldades. Este estudo tem como objetivo avaliar a perceção da inteligência emocional (IE), resiliência (Rs) e stre...
Essential oils from Côa Valley Lamiaceae species: cytotoxicity on glioblastoma ...
Marques, Mário Pedro; Delgado, Jéssica; Zuzarte, Mónica; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Magalhães, Mariana; Cabral, CéliaLavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L) L. subsp. mastichina are widely used and fairly representative species of the flora and traditional uses of the Côa Valley, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are used by local populations to preserve olives, as a condiment in traditional cuisine and to aromatize bonfires on Saint John's Eve, w...