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Burden of disease attributable to risk factors in European countries: a scoping...

Gorasso, Vanessa; Morgado, Joana Nazaré; Charalampous, Periklis; Pires, Sara M.; Haagsma, Juanita A.; Santos, João Vasco; Idavain, Jane; Ngwa, Che Henry

Objectives: Within the framework of the burden of disease (BoD) approach, disease, and injury burden estimates attributable to risk factors are a useful guide for policy formulation and priority setting in disease prevention. Considering the important differences in methods, and their impact on burden estimates, we conducted a scoping literature review to: (1) map the BoD assessments including risk factors perf...


Methodological considerations in injury burden of disease studies across Europe...

Charalampous, Periklis; Pallari, Elena; Gorasso, Vanessa; von der Lippe, Elena; Devleesschauwer, Brecht; Pires, Sara M.; Plass, Dietrich; Idavain, Jane

Background: Calculating the disease burden due to injury is complex, as it requires many methodological choices. Until now, an overview of the methodological design choices that have been made in the burden of disease (BoD) studies in injury populations is not available. The aim of this systematic literature review was to identify existing injury BoD studies undertaken across Europe and to comprehensively revie...


Burden of non-communicable disease studies in Europe: a systematic review of da...

Charalampous, Periklis; Gorasso, Vanessa; Plass, Dietrich; Pires, Sara M; von der Lippe, Elena; Mereke, Alibek; Idavain, Jane

Background: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD ...


Methodological considerations in injury burden of disease studies across Europe...

Charalampous, Periklis; Pallari, Elena; Gorasso, Vanessa; von der Lippe, Elena; Devleesschauwer, Brecht; Pires, Sara M.; Plass, Dietrich; Idavain, Jane

Background: Calculating the disease burden due to injury is complex, as it requires many methodological choices. Until now, an overview of the methodological design choices that have been made in burden of disease (BoD) studies in injury populations is not available. The aim of this systematic literature review was to identify existing injury BoD studies undertaken across Europe and to comprehensively review th...


Burden of non-communicable disease studies in Europe: a systematic review of da...

Charalampous, Periklis; Gorasso, Vanessa; Plass, Dietrich; Pires, Sara M; von der Lippe, Elena; Mereke, Alibek; Idavain, Jane

Background: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD ...


Assessing Scientific Soundness and Translational Value of Animal Studies on DPP...

Franco, Nuno Henrique; Miranda, Sonia Batista; Kovács, Nóra; Nagy, Attila; Thiện, Bùi Quốc; Reis, Flávio; Varga, Orsolya

Although there is a wide range of animal models of type 2 diabetes mellitus (T2DM) used in research; we have limited evidence on their translation value. This paper provides a) a comparison of preclinical animal and clinical results on the effect of five dipeptidyl peptidase-4 (DPP4) inhibitors by comparing the pharmaceutical caused glucose changes, and b) an evaluation of methodological and reporting standards...


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