O presente projeto integrado no plano de estudos do Mestrado em Design de Comunicação da Escola Superior de Arte e Design, em Matosinhos, visa a realização de uma curta metragem de animação para publicação em médias online, designada de “Estudo do Horror em forma de Animação”. O contexto de desenvolvimento deste projeto decorre do facto de ter concluído a pós-graduação de ilustração e animação digital na ESAD, ...
Introduction: Obstructive sleep apnea is a clinical entity that is associated with an increase in morbidity and mortality and it is estimated that it is significantly undiagnosed. The objective of this study was to assess the risk of undiagnosed obstructive sleep apneain obese individuals.Material and Methods: A descriptive and analytical cross-sectional study; the risk of obstructive sleep apnea’s was assessed...
Inherited thrombophilias are a group of clinical conditions in which there is a genetic variant defect associated with a predisposition to thrombosis. Genetic testing for inherited thrombophilias has been used in the diagnosis of specific thrombophila at our centre for the last 20 years, this work will summarize our experience.
The ETF (electron transfer flavoprotein) and ETFDH (ETF dehydrogenase) are flavoproteins involved in electron transfer from primary acyl-CoA dehydrogenases to ubiquinone of the mitochondrial electron transport system (ETS). ETF is a heterodimer composed of subunits ETFα and ETFβand ETFDH is associated to the mitochondrial inner membrane. Electron-donor metabolic reactions in which primary acyl-CoA dehydrogenase...
The Saccharomyces cerevisiae genes YPR004c, YGR207c, YOR356w and YDR036c homologous to human genes involved in transfer of electrons to the respiratory chain from flavin-containing dehydrogenases (ETFA, ETFB and ETFDH) and in beta-oxidation (HADHA), were chosen for characterization. Mutations in ETFA, ETFB and ETFDH (orthologous to YPR004c, YGR207c and YOR356w, respectively) cause multiple acyl-CoA dehydrogenat...