3 documents found, page 1 of 1
Clinical predictors of NEDA-3 one year after diagnosis of pediatric multiple sc...
Palavra, Filipe; Silva, Diogo; Fernandes, Catarina; Faustino, Ricardo; Vasconcelos, Mónica; Pereira, Cristina; Costa, Carmen; Ribeiro, Joana AfonsoIntroduction: Multiple sclerosis (MS) is an inflammatory and demyelinating disorder of central nervous system that can be diagnosed in pediatric age (<18 years) in 3–5% of the cases. This early onset is associated with higher relapse rates and earlier progression to neurological disability. By using NEDA-3 (No Evidence of Disease Activity-3) criteria, we aimed to identify clinical predictors associated with abs...
Inflammatory Activity and Treatment Response in Pediatric Compared to Adult Mul...
de Carvalho, Sara; Pinto, Joana; Correia, Inês; Faustino, Ricardo; Vasconcelos, Mónica; Sousa, Lívia; Palavra, FilipeIntroduction: Pediatric-onset multiple sclerosis may contrast with adult-onset multiple sclerosis, in terms of disease activity. We aimed to determine differentiating features between pediatric-onset multiple sclerosis and adult-onset multiple sclerosis, at diagnosis and after one year under disease modifying therapies, and analyse the attainment of the status of “No Evidence of Disease Activity” between groups...