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Withanolides from leaves of Nicandra physalodes

Carrero, Diego A. S.; Batista, Pedro H. J.; Souza, Luciana G. S.; Pinto, Francisco C. L.; Vasconcelos, Mayron A. de; Teixeira, Edson H.

Five new withanolides, designated as 15-oxo-nicaphysalin B, 6 β ,7 α -dihydroxynicandrenone 10, 24 α ,25 β -dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1 α /1 β -methylpropanone)- nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes . The complete structures of the five new withanolides, particularly their relative stereochemistries, w...

Date: 2018   |   Origin: Oasisbr

Antimicrobial Activity of 3,4- seco -Diterpenes Isolated from Croton blanchetia...

Firmino, Nairley Cardoso Sá; Alexandre, Francisco Serra Oliveira; Vasconcelos, Mayron A. de; Conrado, Alison Jander S.; Arruda, Francisco V. S.

In this study, acid and neutral fractions and three diterpenes were isolated from the hexane extracts from roots of three individual specimens of Croton blanchetianus Baill., collected from the same geographical site. Moreover, the antimicrobial activity of the extracts, fractions and diterpenes isolated was evaluated against Streptococcus mutans and Streptococcus parasanguinis , bacteria related with dental ca...

Date: 2018   |   Origin: Oasisbr

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