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Effect of algae and plant lectins on planktonic growth and biofilm formation in...

Vasconcelos, Mayron Alves; Arruda, Francisco Vassiliepe Sousa; Carneiro, Victor Alves; Silva, H. C.; Nascimento, Kyria Santiago; Sampaio, A. H.

This study aimed to evaluate the abilities of plant and algae lectins to inhibit planktonic growth and biofilm formation in bacteria and yeasts. Initially, ten lectins were tested on Staphylococcus epidermidis, Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Candida albicans, and C. tropicalis at concentrations of 31.25 to 250 μg/mL. The lectins from Cratylia floribunda (CFL), Vatairea macroc...


Antibacterial and antioxidant activities of Derriobtusone A isolated from Lonch...

Vasconcelos, Mayron Alves; Arruda, Francisco Vassiliepe Sousa; Alencar, Daniel Barroso de; Sampaio, Silvana Saker; Albuquerque, Maria Rose Jane Ribeiro

This study evaluated the effect of derriobtusone A, a flavonoid isolated from Lonchocarpus obtusus, on two important pathogenic bacteria, Staphylococcus aureus and Escherichia coli, as well as its antioxidant activity and toxicity. Planktonic growth assays were performed, and the inhibition of biofilm formation was evaluated. In addition, antioxidant activity was assessed by DPPH radical scavenging assay, ferro...


Effect of a casbane diterpene isolated from Croton nepetaefolius on the prevent...

Vasconcelos, Mayron Alves; Arruda, Francisco Vassiliepe Sousa; Santos, Hélcio Silva dos; Rodrigues, Adriano S.; Bandeira, Paulo Nogueira

This study aimed to evaluate the effect of the compound 1,4-dihydroxy-2E,6E,12E-trien-5-one-casbane (CD1CN), a casbane diterpene isolated from Croton nepetaefolius stalks, on the biofilm formation or preformed biofilms of bacteria and yeasts. Minimum inhibitory concentration results showed that CD1CN inhibited the growth of single cultures of Staphylococcus aureus and Candida albicans at 125 and 500 g/mL, respe...


Casbane diterpene activity on mixed biofilms of P. aeruginosa and Candida species

Vasconcelos, Mayron Alves; Lopes, Susana Patrícia; Sousa, Ana Margarida; Santos, Hélcio Silva dos; Bandeira, Paulo Nogueira


Prophylactic outcomes of casbane diterpene in Candida albicans and Candida glab...

Vasconcelos, Mayron Alves; Santos, Hélcio Silva dos; Bandeira, Paulo Nogueira; Albuquerque, Maria Rose Jane Ribeiro; Carneiro, Victor Alves

Biofilms are surface associated communities of microorganisms embedded within a self-produced extracellular matrix and adhered on inert and biotic surfaces. These biological consortia are considered the most prevalent growth form of microorganisms. Biofilm formation is a potent virulence factor for a number of Candida species, as it confers significant tolerance to antimicrobial therapy, primarily by limiting t...


Effect of algae and plant lectins against bacterial biofilm formation

Vasconcelos, Mayron Alves; Arruda, Francisco Vassiliepe Sousa; Carneiro, Victor Alves; Nascimento, Kyria Santiago; Cavada, Benildo Sousa


Antibiofilm effect of some main components of essentials oils on E. coli biofilm

Millezi, A. F.; Vasconcelos, Mayron Alves; Piccoli, R. H.; Oliveira, J. M.; Pereira, Maria Olívia


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