5 documents found, page 1 of 1
Biomarker of Chronic Alcohol Abuse – Carbohydrate-deficient Transferrin (CDT): ...
Gomes, Filomena; Costa, Alcina; Fernandes, Lília; Silva, Ana Maria V. da; Vasconcelos, Miguel; Miranda, ArmandinaIntroduction: Transferrin is a glycoprotein synthesized in hepatocytes that can appear with different isomorphic forms in the plasma, acquiring different levels of sialization (1,2). In a healthy person, penta, tetra and trisial isoforms are detectible in plasma. However, in an alcohol abuse and/or dependence, asialo, monosialo and disialotransferrin isoforms are also present called carbohydrate-deficient trans...
Álbum de Música Portuguesa para Jovens Pianistas
Afonso, Gustavo (coord.); Rosa, António Chagas; Lima, Bernardo; Oliveira, Carla; Vasconcelos, Miguel; Banaco, Paulo; Negreiros, VascoSem resumo disponível.
Development of the HIV360 international core set of outcome measures for adults...
Marques‐Gomes, João; Salt, Matthew J.; Pereira‐Neto, Rita; Barteldes, Franca S.; Gouveia‐Barros, Vera; Carvalho, AlexandreObjectives: HIV outcomes centre primarily around clinical markers with limited focus on patient-reported outcomes. With a global trend towards capturing the outcomes that matter most to patients, there is agreement that standardizing the definition of value in HIV care is key to their incorporation. This study aims to address the lack of routine, standardized data in HIV care. Methods: An international working ...
Biomarcador de alcoolismo crónico – transferrina deficiente em carbohidratos (C...
Gomes, Filomena; Boto, Paulo; Aguiar, Pedro; Vasconcelos, Miguel; Silva, Ana Vieira daNo âmbito da saúde pública torna-se importante compreender a problemática do diagnóstico e monitorização dos doentes com síndrome de dependência do álcool, pelos problemas de saúde e sociais relacionados com o consumo excessivo, mas também pelos custos imputados ao sistema de saúde. Existem vários biomarcadores específicos do alcoolismo, mas na sua maioria ainda não estão devidamente estandardizados, têm limita...
Alcohol Use Disorder
Pinto, Augusto; Fontes Ribeiro, Carlos; Vilar, Graça; Lázaro, José Carlos; Aranda da Silva, José; Trigoso, José Miguel; Cardoso, Manuel; Castro, MárioAlcohol-use disorders (AUD) are a serious public health problem with significant social and economic impact. It is therefore important to discuss the need for a paradigm shift regarding the approach and treatment of AUD. The 5th edition of the «Diagnostic and Statistical Manual of Mental Disorders» (DSM-V) discarded the distinction between harmful alcohol use and alcohol dependence, integrating these concepts i...