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Time course of the effects of lipopolysaccharide on prepulse inhibition and bra...

Custódio, Charllyany Sabino; Mello, Bruna Stefânia Ferreira; Cordeiro, Rafaela Carneiro; Araújo, Fernanda Yvelize Ramos de; Chaves, João Henrique

The systemic administration of lipopolysaccharide (LPS) induces time-dependent behavioral alterations, which are related to sickness behavior and depression. The time-course effects of LPS on prepulse inhibition (PPI) remain unknown. Furthermore, the time-dependent effects of LPS on central nitrite content had not been investigated. Therefore, we studied alterations induced by single LPS (0.5 mg/kg, i.p.) admin...

Date: 2014   |   Origin: Oasisbr
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