Encontrados 24 documentos, a visualizar página 1 de 3
Bridging cyanobacteria to neurodegenerative diseases: A new potential source of...
Castaneda, A; Ferraz, R; Vieira, M; Cardoso, I; Vasconcelos, V; Martins, RNeurodegenerative diseases (NDs) represent a drawback in society given the ageing population. Dementias are the most prevalent NDs, with Alzheimer’s disease (AD) representing around 70% of all cases. The current pharmaceuticals for AD are symptomatic and with no effects on the progression of the disease. Thus, research on molecules with therapeutic relevance has become a major focus for the scientific community...
Isolation and FTIR-ATR and 1H NMR Characterization of Alginates from the Main A...
Belattmania, Z; Kaidi, S; El Atouani, S; Katif, C; Bentiss, F; Jama, C; Reani, A; Sabour, B; Vasconcelos, VAlginates are widely used as gelling agents in textile print pastes, medical industries, impression material in dentistry, and anticoagulant material in toothpaste. In the present study, the content and spectroscopic characterization (1H NMR and FT-IR) of the sodium alginates were investigated in the eight brown seaweeds Sargassum muticum, Fucus vesiculosus f. volubilis, Carpodesmia tamariscifolia, Bifurcaria b...
Putative antimicrobial peptides of the posterior salivary glands from the cepha...
Almeida, D; Domínguez-Pérez, D; Matos, A; Agüero-Chapin, G; Osorio, H; Vasconcelos, V; Campos, A; Antunes, ACephalopods, successful predators, can use a mixture of substances to subdue their prey, becoming interesting sources of bioactive compounds. In addition to neurotoxins and enzymes, the presence of antimicrobial compounds has been reported. Recently, the transcriptome and the whole proteome of the Octopus vulgaris salivary apparatus were released, but the role of some compounds—e.g., histones, antimicrobial pep...
OMICs approaches in diarrhetic shellfish toxins research
Campos, A; Freitas, M; Almeida, AM; Martins, JC; Domínguez-Pérez, D; Osorio, H; Vasconcelos, V; Costa, PRDiarrhetic shellfish toxins (DSTs) are among the most prevalent marine toxins in Europe’s and in other temperate coastal regions. These toxins are produced by several dinoflagellate species; however, the contamination of the marine trophic chain is often attributed to species of the genus Dinophysis. This group of toxins, constituted by okadaic acid (OA) and analogous molecules (dinophysistoxins, DTXs), are hig...
Microcystin Incidence in the Drinking Water of Mozambique: Challenges for Publi...
Tamele, I; Vasconcelos, VMicrocystins (MCs) are cyanotoxins produced mainly by freshwater cyanobacteria, which constitute a threat to public health due to their negative effects on humans, such as gastroenteritis and related diseases, including death. In Mozambique, where only 50% of the people have access to safe drinking water, this hepatotoxin is not monitored, and consequently, the population may be exposed to MCs. The few studies ...
Molecular Responses of Mussel Mytilus galloprovincialis Associated to Accumulat...
Martins, JC; Domínguez-Pérez, D; Azevedo, C; Braga, AC; Costa, PR; Osorio, H; Vasconcelos, V; Campos, AThe molecular pathways behind the toxicity of diarrheic shellfish toxins (DSTs) in bivalves have been scarcely studied. Thus, a shotgun proteomics approach was applied in this work to understand bivalves’ molecular responses to the dinoflagellate Prorocentrum lima (1.0 × 106 cells/L). Protein expression along with toxins levels were analyzed in the gills and digestive gland of the mussel Mytilus galloprovincial...
Shotgun Proteomics of Ascidians Tunic Gives New Insights on Host-Microbe Intera...
Matos, A; Domínguez-Pérez, D; Almeida, D; Aguëro-Chapin, G; Campos, A; Osorio, H; Vasconcelos, V; Antunes, AAscidians are marine invertebrates associated with diverse microbial communities, embedded in their tunic, conferring special ecological and biotechnological relevance to these model organisms used in evolutionary and developmental studies. Next-generation sequencing tools have increased the knowledge of ascidians' associated organisms and their products, but proteomic studies are still scarce. Hence, we explor...
White and red LEDs as two-phase batch for cyanobacterial pigments production
Pagels, F; Lopes, G; Vasconcelos, V; Guedes, A.C.Carotenoids and phycobiliproteins have a high economic value, due to their wide range of biological and industrial applications. The implementation of strategies to increase their production, such as the application of two-phase light cultivation systems, can stimulate pigments production, increasing economic turnover. In this sense, Cyanobium sp. was grown in seven different two-phase white/red cultivation arr...
The Incidence of Tetrodotoxin and Its Analogs in the Indian Ocean and the Red Sea
Tamele, I; Silva, M; Vasconcelos, VTetrodotoxin (TTX) is a potent marine neurotoxin with bacterial origin. To date, around 28 analogs of TTX are known, but only 12 were detected in marine organisms, namely TTX, 11-oxoTTX, 11-deoxyTTX, 11-norTTX-6(R)-ol, 11-norTTX-6(S)-ol, 4-epiTTX, 4,9-anhydroTTX, 5,6,11-trideoxyTTX, 4-CysTTX, 5-deoxyTTX, 5,11-dideoxyTTX, and 6,11-dideoxyTTX. TTX and its derivatives are involved in many cases of seafood poisonin...
The Incidence of Marine Toxins and the Associated Seafood Poisoning Episodes in...
Tamele, I; Silva, M; Vasconcelos, VThe occurrence of Harmful Algal Blooms (HABs) and bacteria can be one of the great threats to public health due to their ability to produce marine toxins (MTs). The most reported MTs include paralytic shellfish toxins (PSTs), amnesic shellfish toxins (ASTs), diarrheic shellfish toxins (DSTs), cyclic imines (CIs), ciguatoxins (CTXs), azaspiracids (AZTs), palytoxin (PlTXs), tetrodotoxins (TTXs) and their analogs,...