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Insights on microalgae-based technologies with potential impact on global metha...

Madureira, Leandro Filipe Feiteira; Soares, Ana Sofia Maciel; Duarte, Maria Salomé Lira; Pereira, Francisco; Francisco, Diogo

The European Unions Methane Action Plan outlined policies and targets supporting the Global Methane Pledge to cut CH4 emissions by 30% by 2030, yet urgent implementation is needed to treat medium and diluted CH4 streams. Microalgae-based technologies offer a groundbreaking solution, merging CH4 mitigation with biomass valorization to drive sustainable industrial practices. This review examines three key applica...


Secondary metabolites of cyanobacteria from Cape Verde Archipelago act as NO do...

Morone, Janaína; Hentschke, Guilherme Scotta; Oliveira, Isabel Benta; Vasconcelos, Vítor; Martins, Rosário; Lopes, Graciliana; Martins, Rosário

Nitric oxide (NO) is a versatile mediator implicated in a variety of physiological processes, with the ultimate goal of maintaining organism homeostasis. In the present work, aqueous extracts from ten cyanobacteria strains isolated from the Cape Verde archipelago were explored as potential NO donors. None of the strains are toxin producers, as demonstrated by PCR and LC-MS analysis. The extracts were mainly com...


Microalgae extracts reduce appetite in zebrafish larvae linked to long-chain fa...

Moxó, Javier Sanz; Fonseca, Ana Catarina; Matos, Gabriela; Saraiva, Jorge; Pereira, Ricardo Nuno Correia; Rocha, Cristina M.R.; Vasconcelos, Vítor

Available online 22 March 2025; Appetite modulation is a promising strategy for obesity treatment. The presented research screened 103 microalgae extracts from three strains of microalgae (Chlorella sp., Chlorococcum sp. and Nannochloropsis oceanica) for appetite reducing activity, using high pressure processing and moderate electric fields. Two different feeding assays with zebrafish larvae were applied using ...


Toxic and non-toxic cyanobacterial biomass as a resource for sustainable agricu...

Massa, Anabella; Santos, Érica; Martins, Diogo; Azevedo, Joana; Reimão, Mariana; Almeida, Agostinho; Azevedo, Rui; Pinto, Edgar; Vasconcelos, Vítor

Cyanobacteria represent a promising resource for sustainable agriculture, as they have demonstrated the ability to restore soil fertility even after death and decay. However, several cyanobacteria can also release secondary metabolites, such as cyanotoxins, which may compromise the quality of agricultural products and pose a potential risk to human health. Depending on the concentration of exposure, few studies...


The neuroprotective role of cyanobacteria with focus on the anti-inflammatory a...

Rodrigues, Flávia; Reis, Mariana; Ferreira, Leonor; Grosso, Clara; Ferraz, Ricardo; Vieira, Mónica; Vasconcelos, Vítor; Martins, Rosário

Neurodegenerative diseases are linked to the process of neurodegeneration. This can be caused by several mechanisms, including inflammation and accumulation of reactive oxygen species. Despite their high incidence, there is still no effective treatment or cure for these diseases. Cyanobacteria have been seen as a possible source for new compounds with anti-inflammatory and antioxidant potential, such as polysac...


Environmentally friendly and cost-effective approaches to reduce toxin content ...

Loss, Letícia; Azevedo, Joana; Azevedo, Tomé; Freitas, Marisa; Vasconcelos, Vítor; Campos, Alexandre

Cyanobacterial outgrowths are naturally occurring processes in eutrophic aquatic ecosystems. Furthermore, as a result of climate change and anthropogenic pollution, cyanobacteria harmful algal blooms (CyanoHABs) are expanding worldwide. CyanoHABs are considered a threat to human health and environment due to the production of potent toxic substances, but at the same time, valuable products can be obtained from ...


Neuroprotective effects of cyanobacterial extracts

Rodrigues, Flávia; Grosso, Clara; Ferreira, Leonor; Vasconcelos, Vítor; Reis, Mariana; Martins, Rosário; Martins, Rosario

Neurodegenerative diseases (ND), namely Alzheimer’s disease (AD) affects millions of people worldwide. Despite their high incidence there is still no effective medical therapy. Cyanobacteria have been in the frontline of the search for therapies for ND. Several in silico, in vitro, and in vivo studies have provided support for the neuroprotective potential of cyanobacterial natural products, particularly in AD....


Evaluation of the anticancer potential of the macrofungus Pisolithus arhizus my...

Santos, Germana; Preto, Marco; Vasconcelos, Vítor; Martins, Rosário; Oliveira, Rui S.; Martins, Rosario

Macrofungi produce remarkable biomedical products that can make a significant contribution to health. Pisolithus arhizus is a fungal species of the phylum Basidiomycota. It is mainly found in association with the roots of some trees species, establishing a mutualistic relationship with them, facilitating the absorption of nutrients from the soil in exchange for carbohydrates produced by the host plant. As recen...


Determination of Vitamin C content in spinach plants grown under the use of cya...

Martins, Diogo; Massa, Anabella; Reimão, Mariana; Vasconcelos, Vítor; Campos, Alexandre; Pinto, Edgar; Freitas, Marisa

The agricultural sector is continuously exploring sustainable and innovative approaches to enhance crop productivity, driving the quest for greener alternatives over synthetic fertilizers. Cyanobacteria have been reported as a promising agricultural fertilizer, with positive effects on crop yield. However, little is known about its potential effects on the produced vegetables' nutritional quality. Studies have ...


Isolation and identification of lichen photobionts collected from different env...

Loureiro, Luís Carlos Sá; Morais, João; Silva, Raquel; Martins, Joana T.; Geada, Pedro Miguel Macedo; Vasconcelos, Vítor; Vicente, A. A.

Lichens are organisms constituted by a symbiotic relationship between a fungus (mycobiont) and a photoautotrophic partner (photobiont). Lichens produce several bioactive compounds; however, the biotechnological exploitation of this organism is hampered by its slow growth. To start studying the possibility of exploiting lichens as alternative sources of bioactive compounds, eighteen lichens were collected in the...


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