6 documents found, page 1 of 1
Quercus spp. extract as a promising preventive or therapeutic strategy for canc...
Oliveira, Paula A.; Vasconcelos-Nóbrega, C; Pires, MJ; Vala, H; Barros, AIRNA; Faustino-Rocha, Ana IAcorns have traditionally been used in the human diet and for the treatment of specific diseases. Therefore, the present study performed a systematic review of studies which investigated the effects of Quercus spp. extracts in cancer prevention and treatment. A systematic literature search was performed for original records which addressed the anticancer effects of Quercus spp. extract in in vitro and in vivo c...
Assessing the in vivo effects of Aloysia citrodora extract: data from K14-HPV16...
Medeiros-Fonseca, B; Vala, H; Vasconcelos-Nóbrega, C; Faustino-Rocha, Ana I; Medeiros, R; Bastos, MMSM; Gil da Costa, RM; Oliveira, PAIntroduction Aloysia citrodora is used in folk medicine in the preparation of infusions due to its antispasmodic, digestive, sedative, and antipyretic properties. It also has antioxidant and antimicrobial properties.The present study evaluated the in vivo efficacy of aqueous extract (AE) of Aloysia citrodora in K14-HPV16 transgenic mice which HPV16 early genomic region and hence develop multiple-step epithelial...
Occupationally Acquired Q Fever in Shepherds and Sheep Milk Cheesemakers
Cruz, R; Santos, C; Esteves, F; Ferreira, AS; Vasconcelos-Nóbrega, C; Mega, C; Albuquerque, C; Teixeira-de-Lemos, E; Coelho, AC; Vala, H; Mesquita, JRQ fever is a zoonosis caused by Coxiella burnetii, and transmission to humans is often associated with contact with ovine and caprine livestock. Those exposed to sheep are particularly at high risk of infection. Recent studies show that Q fever is increasing in sheep farms in Portugal raising alerts on spillover to humans. We detected anti-C. burnetii IgG in shepherds and sheep milk cheesemakers (27 [28.1%] in ...
Bulk-Tank Milk Longitudinal Serosurvey Reveals Decreasing Schmallenberg Virus C...
Esteves, F; Cruz, R; Vasconcelos-Nóbrega, C; Santos, C; Ferreira, AS; Petrovic, T; Cardoso, L; Coelho, AC; Vala, H; Nascimento, MSJ; Mesquita, JRIntroduction: In 2011, Schmallenberg virus (SBV) was first detected in dairy cattle herds in The Netherlands and Germany having since then spread across Europe. Today studies are starting to show a decrease in new SBV infections, a circumstance that raises alerts for possible re-emergence if ideal conditions for vector development occur. To assess the potential decrease in SBV circulation, we performed a 2-year...
Prospective Serosurvey of Coxiella burnetii Antibodies in Selected Sheep of Por...
Cruz, R; Esteves, F; Vasconcelos-Nóbrega, C; Santos, C; Ferreira, AS; Mega, AC; Coelho, AC; Vala, H; Mesquita, JRQ fever is a zoonotic disease caused by Coxiella burnetii that is highly prevalent across the world. In this study, a prospective serosurvey was performed to study C. burnetii circulation in a population of sheep in the central region of Portugal. Blood from a representative sample of 168 animals was drawn in both 2015 and 2016, and sera were tested for IgG anti-C. burnetii by EIA. In 2015, 7.7% (13/168) animal...
Urinary bladder cancer - Old models, new opportunities
Oliveira, PA; Vala, Helena; Gil da Costa, RM; Pinto-Leite, MR; Arantes-Rodrigues, R; Vasconcelos-Nóbrega, CUrinary bladder cancer remains as one of most frequent tumours. To elucidate the reasons for the development of tumours, to find out which factors determine the tumour progression and to develop new and better treatments with fewer side effects, intensive research, with the combination of in vitro and in vivo studies is mandatory. So, in this manuscript we performed a revision concerning the different methodolo...