74 documents found, page 1 of 8
Hereditary breast cancer and ancestry in the Madeira archipelago: An explorator...
Miguel, I; Rodrigues, F; Fragoso, S; Freixo, J; Clara, A; Luís, A; Bento, S; Fernandes, M; Bacelar, F; Câmara, S; Parreira, J; Duarte, T; Rodrigues, PAccess to genetic testing and counselling in remote areas such as the Madeira archipelago, in the Northern Atlantic Ocean, may be complex. Different counselling methods, including telegenetics, should be explored. In this study, we characterise the Hereditary Breast/Ovarian Cancer (HBOC) families with Madeira ancestry enrolled in our programme. Of a total of 3, 566 index patients tested between January 2000 and...
Green tea extract and nanocellulose embedded into polylactic acid film: propert...
Vilarinho, F.; Stanzione, M; Buonocore, G; Vaz, F; Silva, A.S.Eco-friendly and antioxidant bioactive films based on polylactic acid (PLA), loaded with cellulose nanocrystals (CNC) and green tea extract (GTE) were prepared by direct melt processing. GTE was chemically characterized by using high performance liquid chromatography (HPLC), coupled with tandem mass spectrometry. The antioxidant, physical, thermal, mechanical and microstructural properties of the produced films...
Redox–oligomeric state of peroxiredoxin-2 and glyceraldehyde-3-phosphate dehydr...
Valentim-Coelho, C; Vaz, F; Antunes, M; Neves, S; Martins, IL; Osorio, H; Feliciano, A; Pinto, P; Bárbara, C; Penque, DIn this study, we examined the effect of six months of positive airway pressure (PAP) therapy on Obstructive Sleep Apnea (OSA) red blood cell (RBC) proteome by two dimensional difference gel electrophoresis (2D-DIGE)-based proteomics followed by Western blotting (WB) validation. The discovered dysregulated proteins/proteoforms are associated with cell death, H2 O2 catabolic/metabolic process, stress response, a...
Digital Asthenopia: Portuguese Group of Ergophthalmology Survey.
Vaz, F; Henriques, S; Silva, D; Roque, J; Lopes, AS; Mota, MINTRODUCTION: Given the increasing use of electronic devices, and the increasing number of complaints with its use, we intend to evaluate the prevalence of manifestations of dry eye and ocular fatigue in a population of individuals, who use the computer daily to perform all their professional tasks, as well as to correlate these complaints with the number of hours of digital use as well as their possible improv...
Outcomes of Trabeculectomy With and Without Mitomycin C in Pseudoexfoliative Gl...
Lopes, AS; Vaz, F; Henriques, S; Lisboa, M; Vendrell, C; Prieto, IThe aim of this study was to evaluate the outcomes of trabeculectomy with mitomycin C (MMC) in patients with Pseudoexfoliative Glaucoma (PXG) and compare the results with the outcomes of trabeculectomy without MMC in PXG and with MMC in Primary Open Angle Glaucoma (POAG). Ninety eyes (76 patients) submitted to trabeculectomy were included in a one-year retrospective study. Fifty-eight eyes with PXG were divided...
Changes in choroidal thickness following trabeculectomy and its correlation wit...
Silva, D; Lopes, AS; Henriques, S; Lisboa, M; Pinto, S; Vaz, F; Prieto, IPURPOSE: Evaluate whether there are significant changes in choroidal thickness following trabeculectomy, and how they relate do the decline in intraocular pressure. METHODS: This was a prospective evaluation of 28 eyes who underwent Moorfields modified trabeculectomy. The choroidal thickness was measured via OCT with enhanced depth imaging, before surgery and 1 day, 1 week and 1 month after surgery. Measurement...
Comparative study of induced changes in effective lens position and refraction ...
Monteiro, T; Soares, AF; Leite, RD; Franqueira, N; Faria-Correia, F; Vaz, FPURPOSE: To evaluate and compare the changes in refraction and effective intraocular lens (IOL) position between a plate-haptic IOL and a c-loop single-piece IOL after neodymium-doped yttrium aluminium garnet (YAG) laser posterior capsulotomy. METHODS: In a prospective study, anterior chamber depth and subjective refraction were measured in 110 pseudophakic eyes from 110 patients, before and 1 month after YAG l...
Estado Refrativo em Crianças com Retinopatia da Prematuridade Tratada com Laser...
Ramalho, M; Vaz, F; Santos, C; Coutinho, I; Pedrosa, C; Mota, M; Pires, G; Teixeira, Sobjectivo: Relatar o estado refrativo em prematuros que desenvolveram retinopatia da prema- turidade em estadio 3+ e que foram tratados na nossa instituição. material e métodos: Estudo retrospetivo com 24 prematuros em que o tratamento foi de mono- terapia Laser, monoterapia bevacizumab ou combinação de Laser + bevacizumab. Em nove pre- maturos o tratamento num olho foi com monoterapia Laser e no outro olho foi...
Peripapillary Retinal Nerve Fiber Layer Thickness and Peripheral Microcirculati...
Pedrosa, C; Pina, S; Paula, F; Amaral, M; Vaz, FPurpose: Normal-tension glaucoma has been associated with systemic vascular diseases such as peripheral vasospasm. This study aims to evaluate the influence of peripheral vasospasm on the thickness of the retinal nerve fiber layer (RNFL) in Raynaud's disease (RD), and the correlation between global RNFL and peripheral microcirculation features in RD patients. Methods: Observational cross-sectional study of 18 p...
Relação entre a histeresis da córnea e a espessura da lâmina crivosa no glaucom...
Pedrosa, C; Mota, M; Silva, D; Lisboa, M; Almeida, L; Vaz, FObjectivos: Este estudo visa analisar a relação entre a histeresia da córnea (HC) e a espessura da lâmina crivosa (LC) em doentes com glaucoma primário de ângulo aberto (GPAA) e glaucoma pseudoesfoliativo (GPS), comparando também os resultados entre os grupos. Material/Métodos: Estudo transversal que inclui doentes com diagnóstico de GPS e GPAA. Registaram-se os dados demográficos, as espessuras da LC e da cama...