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Hand, Foot, and Mouth Syndrome in an Immunocompetent Adult: a Case Report

Flor de Lima, B; Silva, J; Rodrigues, AC; Grilo, A; Riso, N; Vaz Riscado, M

BACKGROUND: Hand, foot, and mouth syndrome (HFMS) is a common acute illness. It is characterized by mild clinical symptoms including fever, blisters, and sores in the mouth and on the palms and soles following a 3- to 7-day incubation period. This syndrome is rarely seen in adults. CASE PRESENTATION: A 35-year-old male Caucasian patient had a history of multiple episodes of acute pharyngitis, hypertension, hype...


Neuropsychiatric Features of a Cohort of Patients with Systemic Lupus Erythemat...

Moraes-Fontes, MF; Lúcio, I; Santos, C; Campos, MM; Riso, N; Vaz Riscado, M

In order to establish if neuropsychiatric systemic lupus erythematosus (NPSLE) can be identified by any characteristic other than those used to diagnose the neuropsychiatric (NP) disease itself, we retrospectively reviewed 98 systemic lupus erythematosus (SLE) patients followed over a mean period of 10 years. NPSLE was identified in 22 patients. Stroke and generalized seizures were the most frequent NP manifest...


Actinobacillus Endocarditis Associated with Hypertrophic Cardiomyopathy

Jorge, VC; Araújo, AC; Grilo, A; Noronha, C; Panarra, A; Riso, N; Vaz Riscado, M

Infective endocarditis can be associated with complex clinical presentations, sometimes with a difficult multi-disciplinary management. Actinobacillus actinomycetemcomitans belongs to the Haemophilus species, Actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens and Kingella species group, responsible for 5% to 10% of infective endocarditis in native heart valves. These organisms have slow fastidi...


Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge

Jorge, VC; Araújo, AC; Noronha, C; Panarra, A; Riso, N; Vaz Riscado, M

Buerger's disease or Thromboangiitis obliterans is a segmental inflammatory disease that affects the vessels and nerves of the extremities. It usually affects men below 45 years old and correlates with tobacco, as a predisposing factor. The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance....


Wegener's Granulomatosis: Skin Deep

Pires Silva, I; Noronha, C; Panarra, A; Riso, N; Vaz Riscado, M


No Pulse: a Medical Conundrum

Pires Silva, I; Noronha, C; Panarra, A; Riso, N; Vaz Riscado, M


Stress-Related Mucosal Disease: Incidence of Bleeding and the Role of Omeprazol...

Amaral, M; Favas, C; Delgado Alves, J; Riso, N; Vaz Riscado, M

BACKGROUND: Upper gastrointestinal bleeding is the severe complication of stress-related mucosal disease in hospitalized patients. In intensive care units (ICU), risk factors are well defined and only mechanical ventilation and coagulopathy proved to be relevant for significant bleeding. On the contrary, in non-ICU settings there is no consensus about this issue. Nevertheless, omeprazole is still widely used in...


Personality, Brain Asymmetry, and Neuroendocrine Reactivity in Two Immune-Media...

Martin Martins, J; Alves, J; Trinca, A; Grima, B; Vale, S; Vasconcelos, T; Riso, N; Vaz Riscado, M; Charneco da Costa, J

Development of some immune-mediated disorders may depend on dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. To explore neuropsychologic mechanisms in relation to the abnormal endocrine reactivity in patients with systemic lupus erythematosus (SLE) and chronic hepatitis C (CHC) we used the corticotropin releasing hormone (CRH) test, the Minnesota Multiphasic Personality Inventory (MMPI), and the ...


Lúpus Eritematoso Disseminado. Revisão de 20 Casos

Ferreira, F; Martins, J; Riso, N; Soromenho, F; Vaz Riscado, M; Monteiro Baptista, L

Os autores reviram 20 casos de L.E.D. estudados no Serviço de 1982 a 1985, sujeitaram-nos a um protocolo baseado nos critérios estabelecidos pela A.R.A. para o diagnóstico desta doença e comentaram, à luz da literatura actualmente disponível, os seus achados clínico-laboratoriais.


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