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Comparison of protocols for removal of melanin from genomic DNA to optimize PCR...

Vicente, Anna Luiza Silva Almeida; Bianchini, Raquel Alves; Laus, Ana Carolina; Macedo, Graziela; Reis, R. M.; Vazquez, Vinicius de Lima

Melanin is produced by melanocytes and protects against DNA damage by ultraviolet light. Unfortunately, the melanin protein present in melanoma tumor cells is often co-purified during DNA extraction, and this contamination may inhibit subsequent PCR methods, which directly impacts research applications and the molecular diagnostic tests needed for targeted therapeutics. There are presently no described purifica...

Date: 2019   |   Origin: RepositóriUM - Universidade do Minho
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The Hospital de Câncer de Barretos Registry: an analysis of cancer survival at ...

Carneseca, Estela Cristina; Mauad, Edmundo Carvalho; de Araujo, Marcos Aurélio Alves; Dalbó, Rafael Macrina; Longatto, Adhemar

Epidemiological studies that describe cancer survival statistics at specific hospitals are scarce. Cancer registries, which are collections of cancer patient characteristics, treatment and outcome data, help determine quality of care and treatment indicators.

Date: 2013   |   Origin: RepositóriUM - Universidade do Minho
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