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Striatal dopamine D2-like receptors availability in obesity and its modulation ...
Ribeiro, Gabriela; Maia, Ana; Cotovio, Gonçalo; Oliveira, Francisco P.M.; Costa, Durval C.; Oliveira-Maia, AJOK; There is significant evidence linking a 'reward deficiency syndrome' (RDS), comprising decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like behaviors underlying substance use disorders and obesity. Regarding obesity, a systematic review of the literature with a meta-analysis of such data is lacking. Following a systematic review of the literature, we performed random-effe...
Motor cortical inhibitory deficits in patients with obsessive-compulsive disord...
Rodrigues da Silva, Daniel; Maia, Ana; Cotovio, Gonçalo; Oliveira, José; Oliveira-Maia, AJ; Barahona-Corrêa, J. BernardoFunding Information: DR was supported by H2020-SC1-DTH-2019-875358-FAITH. AM and GC are supported by Fundação para a Ciência e Tecnologia (FCT) through Ph.D. Scholarships (respectively, SFRH/BD/144508/2019 and SFRH/BD/130210/2017). GC and AO-M are supported by grant FCT-PTDC/MED-NEU/31331/2017, funded by FCT/MCTES. AO-M was funded by a Starting Grant from the European Research Council under the European Union’s...
Diagnosis and Treatment of Neuroleptic Malignant Syndrome in the Intensive Care...
Maia, Ana; Cotovio, Goncalo; Barahona-Correa, Bernardo; Oliveira-Maia, AJNeuroleptic malignant syndrome is a neurological emergency caused by dysregulation of dopaminergic neurotransmission. While it is typically characterized by muscle rigidity, fever and altered mental status, it may have a heterogeneous and non-specific presentation, leading to delays in diagnosis and treatment. Treatment involves cessation of dopamine-receptor antagonists and supportive measures, but in more sev...