The development of innovative bio-based skin care products has received an increase attention in the latter years. In the present work, the synthesis of original active principle ingredients based ionic liquids (ILs) with cholinium cation and vitamins B anions followed by their incorporation in bacterial nanocellulose (BC) membranes for topical applications is reported. Three ILs, namely cholinium nicotinate [C...
The development of innovative bio-based skin care products has received an increased attention in the latter years. In the present work, the synthesis of original active principle ingredients based on ionic liquids (ILs) with cholinium cation and vitamins B anions, followed by their incorporation in bacterial nanocellulose (BC) membranes for topical applications, is reported. Three ILs, namely choliniumnicotina...
Introduction: Blueberries have been associated with several potentially beneficial properties including antioxidant and anti-inflammatory activity and, more recently, with the modulation of the intestinal microbiota. Gut microbiota is considered as essential for the normal functioning of the body and the maintenance of health, with the connection between gut microbiota composition of the intestinal microbiota a...
Over the last two decades worldwide levels of antibiotic resistance have risen leading to the appearance of multidrug resistant microorganisms. Acinetobacter baumannii is a known skin pathogen which has emerged as a major cause of nosocomial outbreaks due to its capacity to colonize indwelling medical devices and natural antibiotic resistance. With chitosan being an effective antimicrobial agent against antibio...
Chitosan is a biocompatible, bioactive, non-toxic polymer that due to these characteristics has been widely used as a carrier for targeted delivery of bioactive molecules. In recent years, and considering that chitosan has a strong antimicrobial potential, the scientific community's focus has shifted onto the possible antimicrobial activity of chitosan nanoparticles. With this in mind, the aim of this work was ...
Introdução: A esofagite herpética é uma doença frequente em doentes imunodeprimidos, sendo raros os casos descritos em indivíduos imunocompetentes. Caso clínico: Os autores descrevem o caso de uma adolescente, admitida no serviço de urgência com febre, odinofagia, disfagia para líquidos e sólidos e dor retroesternal, com três dias de evolução. Realizou endoscopia digestiva alta, que revelou erosões lineares e r...
Vivemos num mundo cada vez mais globalizado e uma das consequências é a crescente concorrência que existe entre territórios, reforçando-se a necessidade de fazer chegar aos públicos interessados, um conjunto de atributos e diferenciações, suficientemente atrativos e apelativos, para que estes territórios sejam “consumidos”, não só pelo seu reconhecimento temporal, mas também pela forma como ele se comunica. Se ...