Encontrados 4 documentos, a visualizar página 1 de 1
Petrosamine isolated from marine sponge Petrosia sp. demonstrates protection ag...
RIbeiro, Joana Francisca Marinho Parente; Araújo-Silva, Henrique; Fernandes, Mário; Silva, Joilna Alves; Pinto, Francisco das Chagas L.According to The World Alzheimer Report 2023 by Alzheimer’s Disease International (ADI) estimates that 33 to 38.5 million people worldwide suffer from Alzheimer’s Disease (AD). A crucial hallmark associated with this disease is associated with the deficiency of the brain neurotransmitter acetylcholine, due to an affected acetylcholinesterase (AChE) activity. Marine organisms synthesize several classes of compou...
Lyotropic liquid crystalline 2D and 3D mesophases: advanced materials for multi...
Araújo-Silva, Henrique; Teixeira, Patricia V.; Gomes, Andreia C.; Lúcio, Marlene; Lopes, Carla MartinsCancer remains a leading cause of mortality. Despite significant breakthroughs in conventional therapies, treatment is still far from ideal due to high toxicity in normal tissues and therapeutic inefficiency caused by short drug lifetime in the body and resistance mechanisms. Current research moves towards the development of multifunctional nanosystems for delivery of chemotherapeutic drugs, bioactives and/or r...
Lyotropic liquid crystalline 2D and 3D mesophases: Advanced materials for multi...
Araújo-Silva, Henrique; Teixeira, Patricia V; Gomes, Andreia C; Lúcio, M.; Lopes, Carla MCancer remains a leading cause of mortality. Despite significant breakthroughs in conventional therapies, treatment is still far from ideal due to high toxicity in normal tissues and therapeutic inefficiency caused by short drug lifetime in the body and resistance mechanisms. Current research moves towards the development of multifunctional nanosystems for delivery of chemotherapeutic drugs, bioactives and/or r...
Retinoic acid: a key regulator of lung development
Fernandes-Silva, Hugo; Araújo-Silva, Henrique; Correia-Pinto, Jorge; Moura, Rute SRetinoic acid (RA) is a key molecular player in embryogenesis and adult tissue homeostasis. In embryo development, RA plays a crucial role in the formation of different organ systems, namely, the respiratory system. During lung development, there is a spatiotemporal regulation of RA levels that assures the formation of a fully functional organ. RA signaling influences lung specification, branching morphogenesis...