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Endocrine disruption effects of p,p'-DDE on juvenile zebrafish

Monteiro, Marta Sofia; Pavlaki, Maria; Faustino, Augusto; Rêma, Alexandra; Franchi, Mariana; Gediel, Letícia; Loureiro, Susana; Domingues, Inês

The persistent organic pollutant p,p′-DDE, the major metabolite of the insecticide DDT, has displayed evidence of endocrine disruption through the inhibition of androgen binding to androgen receptors in different species. Although p,p′-DDE was continuously detected in wild fish with abnormal gonad development such as intersex, little is known about its mode of action during gonad development in fish. To elucida...

Date: 2015   |   Origin: RIA - Repositório Institucional da Universidade de Aveiro
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