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Evaluation of anxiolytic-like effect of 7-epiclusianone isolated from Garcinia ...

Veloso, Clarice de Carvalho; Silva, Mayara Bueno da; Megda, Marianne de Oliveira; Santos, Marcelo Henrique dos; Giusti-Paiva, Alexandre

Garcinia brasiliensis Mart., Clusiaceae, species became the target of studies for some years because it has several compounds including polyprenylated benzophenones, as 7-epiclusianone. This benzophenone has several properties, such as leishmanicidal, anti-inflammatory and antinociceptive effects, however still did not be studied anxiolytic activity. For this, the open field and elevated plus maze tests were us...

Date: 2019   |   Origin: Oasisbr
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