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Ocimum basilicum leaf essential oil and (-)-linalool reduce orofacial nocicepti...
Venâncio, Antônio Medeiros; Marchioro, Murilo; Estevam, Charles dos Santos; Melo, Mônica Santos de; Santana, Marília Trindade deThe present study investigated the antinociceptive effects of Ocimum basilicum L. (Lamiaceae) leaf essential oil (LEO) and (-)-linalool (LIN) in formalin (2%)-, glutamate (25 µM)- and capsaicin (2.5 µg)- induced orofacial nociception models in mice. The involvement of these substances was further evaluated on the neuronal excitability of the hippocampal dentate gyrus. Male mice (n=8/group) were pretreated separ...
Data: 2013
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Origem: Oasisbr