19 documents found, page 1 of 2
Tackling water contamination by oncologic drugs: supported ionic liquids as sus...
Francisco, Rafael; Monteiro, Bruna; Santos, Maria J.; Silva, Francisca A. e; Venâncio, Cátia; Neves, Márcia C.; Lopes, Isabel; Sousa, Ana C. A.Due to the increasing incidence of cancer, the consumption of highly toxic oncological drugs is continuously growing. Given the current lack of efficient technologies to remove/treat these toxic drugs in wastewater treatment plants, the environmental quality is compromised, and aquatic organisms are at risk. To address this critical environmental burden, a new strategy based on supported ionic liquids (SILs) fo...
Adding knowledge to the design of safer hydrophobically modified poly(acrylic) ...
Tavares, Jorge; Venâncio, Cátia; Duarte, Cláudia Margarida Gouveia; Antunes, Filipe E.; Lopes, IsabelThe architecture of hydrophobically modified polymers can be tailored to produce variants with different levels of functionality. This allows industry to apply rational design methods for the development of more environmentally friendly materials. In the present work, the ecotoxicity of six variants of hydrophobically modified poly(acrylic) acids (HMPAA), obtained by changing the crosslinked conformation, inser...
Knowledge, concerns and attitudes towards plastic pollution: An empirical study...
Santos, Ana; Venâncio, Cátia; Oliveira, Miguel; Miguel, IsabelWhile the harmful effects of different types of plastic particles have been increasingly reported, studies on public perceptions and behaviors related to plastic pollution may be considered limited. The present study aims to assess the general public's knowledge, awareness, and concern about plastic pollution in different environmental compartments (air, water, and soil) and assess recycling behaviors. For this...
Assessing the risks of capecitabine and its active metabolite 5-fluorouracil to...
Venâncio, Cátia; Monteiro, Bruna; Lopes, Isabel; Sousa, Ana CatarinaCapecitabine (CAP, prodrug) and 5-fluorouracil (5-FU, its active metabolite) are two of the most prominent cytostatics, for which no clear picture can be drawn regarding potential concentrations of effect for freshwater biota, with CAP being grouped in the least studied cytostatic, whereas 5-FU has been classified as of no and of high environmental risk. Accordingly, the present work aimed to assess the ecotoxi...
Ecotoxicological Tools to Assess Cytostatic Effects in Freshwater Environments:...
Venâncio, Cátia; Monteiro, Bruna; Francisco, Rafael; Neves, Márcia C; Freire, Mara G; Sousa, Ana C A; Lopes, IsabelGiven the growing number of cancer diseases, new cytostatic drugs are approved daily, often with concomitant development, or refinement of some of these drugs aimed at decreasing patient discomfort during the administration period (e.g., prodrugs). Classified as highly toxic, they represent a major environmental problem that may potentiate disease occurrences. For newer cytostatic and prodrugs there are no (or ...
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for...
Santos, Ana; Oliveira, Miguel; Venâncio, CátiaNanoplastics (NPLs) accumulated in freshwater systems may serve as sinks for metal(loid)s. To date, few studies have assessed the joint effects of NPLs-metal(loid)s on freshwater biota and the risk that these mixtures may pose has not been discussed. This critical review shows that research in this context focused solely on a single polymer – polystyrene, and single shape – spherical particles, in combination w...
Nanoplastics and biota behaviour: known effects, environmental relevance, and r...
Ferreira, Carla S.S.; Venâncio, Cátia; Oliveira, MiguelBehaviour is increasingly recognized as a sensitive screening tool to detect the effects of environmental disturbances on biota, resulting from molecular, biochemical, and physiological processes. In this sense, several (eco)toxicological studies have been assessing and reporting the behavioural effects of xenobiotics, even at very low doses. Different behavioural endpoints may help to estimate more accurately ...
Contributions towards the hazard evaluation of two widely used cytostatic drugs
Monteiro, Bruna; Venâncio, Cátia; Francisco, Rafael; Sousa, Ana Catarina A.; Lopes, IsabelCytostatic drugs are one of the most important therapeutic options for cancer, a disease that is expected to affect 29 million individuals by 2040. After being excreted, cytostatics reach wastewater treatment plants (WWTPs), which are unable to efficiently remove them, and consequently, they will be released into the aquatic environment. Due to the highly toxic properties of cytostatics, it is particularly rele...
Bioplastics: known effects and potential consequences to marine and estuarine e...
Venâncio, Cátia; Lopes, Isabel M. C. A.; Oliveira, MiguelBioplastics have been suggested as more sustainable alternatives to conventional, petroleum-based plastics. In this work, the available studies comparing effects of biopolymers and petroleum-based plastics were reviewed to improve the knowledge on the sustainability of biobased polymers, providing a benchmark regarding their ecotoxicological effects, as well as to highlight research priorities in this field. Th...
On the path to minimize plastic pollution: The perceived importance of educatio...
Soares, Joana; Venâncio, Cátia; Lopes, Isabel; Oliveira, Marcelino; Miguel, IsabelEnvironmental awareness and education have been recognized as tools to help mitigate environmental issues. This study, performed in Portugal, aimed to describe perceived factors building environmental awareness on plastic pollution, study how perceptions are influenced by sociodemographic characteristics, and identify perceived priority targets for intervention. Results showed that participants recognize societ...