44 documents found, page 1 of 5
Hepatocellular Early Apoptosis Associated with HES 130/0.4 Administration for V...
Vala, Helena; Faustino-Rocha, Ana I; Curz, Rita; Venâncio, Carlos; Silva, Aura; Mesquita, João R; Ortiz, Ana L; Ferreira, David AHydroxyethyl starch 130/0.4 is a colloid solution used for expanding the plasma volume in situations of severe hypotension that, for example, may result from acute severe blood loss. This volume expansion allows for a more adequate organ perfusion, and consequent oxygen and nutrient delivery to the tissues. Nevertheless, several secondary effects associated with the hydroxyethyl starch 130/0.4 administration ha...
Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesi...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana; Silva, Jessica; Silva, Mónica; Pires, Maria João; Neuparth, Maria João; Vala, HelenaAloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, WT, 0...
Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
Fernandes, Filipa Alexandra; Oliveira, Paula A.; Pinto, M.L.; Venâncio, Carlos; Félix, Luís; Medeiros-Fonseca, Beatriz; Correia, RossanaThis work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second e...
Exploring the therapeutic potential of Quercus ilex acorn extract in papillomav...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Vasconcelos-Nóbrega, Cármen; Gouvinhas, IrenePapillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have several unexplored ...
Exploring the therapeutic potential of Quercus ilex acorn extract in papillomav...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I.; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Nóbrega, Carmen; Gouvinhas, IreneBackground and Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have...
Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesi...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I.; Silva, Jéssica; Silva, Mónica G.; Pires, Maria João; Neuparth, Maria João; Vala, HelenaAim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, ...
loysia citrodora extract as a chemopreventive agent against HPV16-induced lesio...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I; Silva, Jessica; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Vasconcelos-Nóbrega, CarmenAim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, ...
Relation between infrared thermometry and thermal imaging for assessment of rod...
Oliveira, Paula A.; Gonçalves, Lio; Gonçalves, Mariana; Venâncio, Carlos; Azevedo, Tiago; Ribeiro, Carla; Reis, Rita; Faustino-Rocha, Ana IAnimals have been used for biomedical research since ancient times. Humane endpoints have been increasingly implemented during experimental protocols to prevent or alleviate animals’ suffering. Body temperature is an indicator of stress or anxiety. Infrared thermometer (IRT) and infrared thermal imaging camera (TIC) are commercially available for temperature measurement. This study aimed to determine mice and r...
Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell D...
Castelão-Baptista, José P.; Valente, Sara A.; Canário, Sara; Oppolzer, David; Barros, Ana; Venâncio, Carlos; Martins, Tânia; Antunes, LuísObesity, a rising concern in the Eastern world, encompasses several co-morbidities, namely non-alcoholic fatty liver disease (NAFLD). Potential natural-based interventions to decrease the burden of obesity complications are being investigated. Many of the edible parts of plants are not sold for consumption and end up as massive waste, losing nutritional potential. In fact, a sizeable amount of waste is generate...
Supplementation of an anthocyanin-rich elderberry (Sambucus nigra L.) extract i...
Azevedo, Tiago; Ferreira, Tiago; Ferreira, João Miguel Mendes; Teixeira, Filipa; Ferreira, Diana; Silva-Reis, Rita; Neuparth, Maria JoãoFeatured Application Due to anthocyanins' potential as colorants, this anthocyanin-rich elderberry extract presents a healthier alternative to commercially available colorants and has the potential to be used at industry level. Sambucus nigra L., popularly known as elderberry, is renowned for its amazing therapeutic properties, as well as its uses as a food source, in nutraceuticals, and in traditional medicine...