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Genetic variants in the IL1A gene region contribute to intestinal-type gastric ...
Durães, C; Muñoz, X; Bonet, C; García, N; Venceslá, A; Carneiro, F; Peleteiro, B; Lunet, N; Barros, H; Lindkvist, B; Boutron-Ruault, M-CThe most studied genetic susceptibility factors involved in gastric carcinoma (GC) risk are polymorphisms in the inflammation-linked genes interleukin 1 (IL1) B and IL1RN. Despite the evidence pointing to the IL1 region, definite functional variants reproducible across populations of different genetic background have not been discovered so far. A high density linkage disequilibrium (LD) map of the IL1 gene clus...
Date: 2014
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Origin: Repositório Aberto da Universidade do Porto