3 documents found, page 1 of 1
Improving preparedness to respond to cross-border hepatitis A outbreaks in the ...
Enkirch, T.; Severi, E.; Vennema, H.; Thornton, L.; Dean, J.; Borg, M.L.; Ciccaglione, A.R.; Bruni, R.; Christova, I.; Ngui, S.L.; Balogun, K.Sequence-based typing of hepatitis A virus (HAV) is important for outbreak detection, investigation and surveillance. In 2013, sequencing was central to resolving a large European Union (EU)wide outbreak related to frozen berries. However, as the sequenced HAV genome regions were only partly comparable between countries, results were not always conclusive. Aim: The objective was to gather information on HAV sur...
Usability of the international HAVNet hepatitis A virus database for geographic...
Kroneman, A.; de Sousa, R.; Verhoef, L.; Koopmans, M.P.G.; Vennema, H.; On Behalf Of The HAVNet NetworkBackground:HAVNet is an international laboratory network sharing sequences and corresponding metadata on hepatitis A virus in an online database. Aim: We give an overview of the epidemiological and genetic data and assess the usability of the present dataset for geographical annotation, backtracing and outbreak detection. Methods: A descriptive analysis was performed on the timeliness, completeness, epidemiolog...
Hepatitis A outbreak disproportionately affecting men who have sex with men (MS...
Ndumbi, P.; Freidl, G.S.; Williams, C.J.; Mårdh, O.; Varela, C.; Avellón, A.; Friesema, I.; Vennema, H.; Beebeejaun, K.; Ngui, S.L.; Edelstein, M.Between 1 June 2016 and 31 May 2017, 17 European Union (EU) and European Economic Area countries reported 4,096 cases associated with a multi-country hepatitis A (HA) outbreak. Molecular analysis identified three co-circulating hepatitis A virus (HAV) strains of genotype IA: VRD_521_2016, V16-25801 and RIVM-HAV16-090. We categorised cases as confirmed, probable or possible, according to the EU outbreak case def...