Made available in DSpace on 2022-04-28T19:42:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01; INTRODUCTION: Chronic kidney disease - mineral and bone disorders (CKD-MBD) are common in dialysis patients. Definition of targets for calcium (Ca), phosphorus (P), parathormone (iPTH), and alkaline phosphatase (ALP) and their treatment recommendations, are provided by international guidelines. There ar...
Made available in DSpace on 2018-12-11T17:13:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-07-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade de São Paulo; Background Observational studies have shown a beneficial effect of obesity on bone health; however, most of those studies were not based on bone biopsies. Metabolic syndrome (MetS) could have an effect on bone remo...
OBJECTIVES: The present study was designed to evaluate the bone phenotypes and mechanisms involved in bone disorders associated with hepatic osteodystrophy. Hepatocellular disease was induced by carbon tetrachloride (CCl4). In addition, the effects of disodium pamidronate on bone tissue were evaluated. METHODS: The study included 4 groups of 15 mice: a) C = mice subjected to vehicle injections; b) C+P = mice su...
OBJECTIVES: Recent studies have shown a high prevalence of hypovitaminosis D, defined as a serum 25-hydroxyvitamin D level less than 30 ng/ml, in both healthy populations and patients with chronic kidney disease. Patients undergoing kidney transplant are at an increased risk of skin cancer and are advised to avoid sunlight exposure. Therefore, these patients might share two major risk factors for hypovitaminosi...
Made available in DSpace on 2015-12-07T15:31:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2014. Added 1 bitstream(s) on 2015-12-07T15:53:09Z : No. of bitstreams: 1 PMC3924878.pdf: 1349269 bytes, checksum: e6faec8aa60fb89e4b03f61e8547bc68 (MD5); New strategies to fulfill craniofacial bone defects have gained attention in recent years due to the morbidity of autologous bone graft harvesting. We aimed to e...