16 documents found, page 1 of 2
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Veríssimo, Manuel T.; Dourado, MaríliaPain is one of the most frequent health problems, and its evaluation and therapeutic approach largely depend on patient self-report. When it is not possible to obtain a self-report, the therapeutic decision becomes more difficult and limited. This study aims to evaluate whether some membrane platelet proteins could be of value in pain characterization. To achieve this goal, we used 53 blood samples obtained fro...
Monocytes in the Characterization of Pain in Palliative Patients with Severe De...
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Veríssimo, Manuel T.; Andrade, José PauloIn assessing and managing pain, when obtaining a self-report is impossible, therapeutic decision-making becomes more challenging. This study aimed to investigate whether monocytes and some membrane monocyte proteins, identified as a cluster of differentiation (CD), could be potential non-invasive peripheral biomarkers in identifying and characterizing pain in patients with severe dementia. We used 53 blood samp...
A Universal Pharmacological-Based List of Drugs with Anticholinergic Activity
Lavrador, Marta; Cabral, Ana C.; Veríssimo, Manuel T.; Fernandez-Llimos, Fernando; Figueiredo, Isabel V.; Castel-Branco, M. MargaridaAnticholinergic burden tools have relevant pharmacological gaps that may explain their limited predictive ability for clinical outcomes. The aim of this study was to provide a universal pharmacological-based list of drugs with their documented affinity for muscarinic receptors. A comprehensive literature review was performed to identify the anticholinergic burden tools. Drugs included in these instruments were ...
Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting presc...
Ribeiro, Hugo; Rodrigues, Inês; Napoleão, Leonardo; Lira, Luís; Marques, Denise; Veríssimo, Manuel T.; Andrade, José Paulo; Dourado, MaríliaA narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms "pharmacokinetics", "ibuprofen", "diclofenac", "acemetacin", "naproxen", "etodolac" and "etoricoxib" was performed. From 828 articles identified, only eight met the inclusion criteria. Selective COX-2 inhibitors are associated with higher cardiovascular risk, while non-selec...
COMBINING DIFFERENT CONCURRENT TRAINING METHODS IN OLDER ADULTS WITH METABOLIC ...
Silva, Marco Antonio R. da; França, Elias de; Baptista, Liliana C.; Neves, Rafael S.; Loureiro, Helena; Caperuto, Erico C.; Veríssimo, Manuel T.Introduction: There are no studies comparing the effects of different concurrent training routines [i.e., a resistance training plus high-intensity interval training (RT+HIIT) program compared to an RT plus moderate- intensity continuous training (RT+MICT) program] on cardiorespiratory fitness (CRF) and physical performance in older adults with metabolic syndrome (MetS). Objectives: This study aimed to compare ...
Association between anticholinergic burden and anticholinergic adverse outcomes...
Lavrador, Marta; Castel-Branco, M. Margarida; Cabral, Ana C.; Veríssimo, Manuel T.; Figueiredo, Isabel V.; Fernandez-Llimos, FernandoThe use of anticholinergic drugs and other drugs with anticholinergic activity is highly prevalent in older people. Cumulative anticholinergic effects, known as anticholinergic burden, are associated with important peripheral and central adverse effects and outcomes. Several methods have been developed to quantify anticholinergic burden and to estimate the risk of adverse anticholinergic effects. Serum antichol...
Os custos da aterosclerose em Portugal
Costa, João; Alarcão, Joana; Amaral‐Silva, Alexandre; Araújo, Francisco; Ascenção, Raquel; Caldeira, Daniel; Cardoso, Marta Ferreira; Correia, ManuelIntrodução e objetivos: As doenças cardiovasculares são a principal causa de morte em Portu-gal, sendo a aterosclerose o processo fisiopatológico subjacente mais comum. O objetivo desteestudo foi quantificar o impacto económico da aterosclerose em Portugal através da estimac¸ãodos custos associados.Métodos: A estimativa dos custos foi realizada na ótica da prevalência e na perspetiva dasociedade. A prevalência ...
Size of the associations between anticholinergic burden tool scores and adverse...
Lavrador, Marta; Cabral, Ana C.; Figueiredo, Isabel V.; Veríssimo, Manuel T.; Castel-Branco, M. Margarida; Fernandez-Llimos, Fernando3910-3178-31BA | MARIA MARGARIDA COUTINHO DE SEABRA CASTEL-BRANCO CAETANO; info:eu-repo/semantics/publishedVersion
The Effects of Concurrent Training Combining Both Resistance Exercise and High-...
Silva, Marco Antônio R. da; Baptista, Liliana C.; Neves, Rafael S.; De França, Elias; Loureiro, Helena; de Lira, Fábio Santos; Caperuto, Erico C.To date, there are several knowledge gaps on how to properly prescribe concurrent training to achieve the best dose-response, especially regarding the optimal intensity or volume of the aerobic component. Thus, the objective of this study is to analyze the effects of different aerobic exercise modes and intensities [i.e. aerobic high-intensity interval training (HIIT) versus moderate-intensity continuous aerobi...
The Effects of Concurrent Training Combining Both Resistance Exercise and High-...
Da Silva, Marco Antônio R.; Baptista, Liliana C.; Neves, Rafael S.; De França, Elias; Loureiro, Helena; Lira, Fabio Santos [UNESP]; Caperuto, Erico C.Made available in DSpace on 2020-12-12T01:29:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-11; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); To date, there are several knowledge gaps on how to properly prescribe concurrent training to achieve the best dose-response, especially regarding the optimal intensity or volume of the aerobic component. Thus, the objective of this study is...