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Etiology and severity of diarrheal diseases in infants at the semiarid region o...

Lima, Aldo A. M.; Oliveira, Domingos B.; Quetz, Josiane S.; Havt, Alexandre; Prata, Mara M. G.; Lima, Ila F. N.; Soares, Alberto M.; Q. Filho, José

Background Diarrheal diseases are an important cause of morbidity and mortality among children in developing countries. We aimed to study the etiology and severity of diarrhea in children living in the low-income semiarid region of Brazil. Methodology This is a cross-sectional, age-matched case-control study of diarrhea in children aged 2–36 months from six cities in Brazil’s semiarid region. Clinical, epidemio...

Date: 2019   |   Origin: Oasisbr

Intestinal cell migration damage induced by enteropathogenic Escherichia coli s...

Cavalcante, Paloma A.; Prata, M. M. G.; Medeiros, Pedro Henrique Quintela Soares; Silva, A.V. Alves da; Quetz, Josiane S.

Epithelial cell migration is an essential response to enteric pathogens such as enteropathogenic Escherichia coli (EPEC). This study aimed to investigate the effects of EPEC infection on intestinal epithelial cell migration in vitro, as well as the involvement of type III secretion system (T3SS) and Rho GTPases. Crypt intestinal epithelial cells (IEC-6) were infected with EPEC strains (E2348/69, DescF, and the ...

Date: 2019   |   Origin: Oasisbr

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