4 documents found, page 1 of 1
Ponderal behavior of rats fed an omegas 3, 6 and 9 enriched diet submitted to c...
Burlamaqui,Idália Maria Brasil; Dornelas,Conceição Aparecida; Brito,Lara Albuquerque de; Trindade Júnior,José Wilson Meireles; Sucupira,Rafael Moura ePURPOSE: To assess weight changes in rats fed diets with different ratios of omegas 3, 6 and 9 submitted to colonic carcinogenesis induced by Azoxymethane (AOM). METHODS: Sixty rats with three weeks of life were distributed into five groups of specific diets containing 12 animals each: GI- Standard diet without adminstration of AOM, GII- Standard diet with adminstration of AOM; GIII- Hyperlipidic diet with admi...
Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano
Burlamaqui,Idália Maria Brasil; Dornelas,Conceição Aparecida; Almeida,Paulo Roberto Carvalho; Jamacaru,Francisco Vagnaldo FechineOBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas no início do experimento. No grupo 1, receberam 1.0mL de solução salina intraperitonealmente uma vez por semana por duas semanas. No grupo 2, receberam 15 mg/k...
Effect of a hyperlipidic diet rich in omegas 3, 6 and 9 on aberrant crypt forma...
Burlamaqui,Idália Maria Brasil; Dornelas,Conceição Aparecida; Valença Júnior,José Telmo; Mota,Daniel Magalhães Coutinho; Mesquita,Francisco José CabralPURPOSE: To determine whether a hypercaloric and hyperlipidic diet enriched with polyunsaturated fatty acids influences the formation of aberrant crypt foci (ACF) in colonic mucosa of Wistar rats treated with azoxymethane (AOM). METHODS: At eight weeks of life, the rats were assigned to four groups: Group I―standard diet (STD) not treated with AOM; Group II―hypercaloric and hyperlipidic diet (FED), not treated ...
Optimization of visibility and quantification of aberrant crypt foci in colonic...
Burlamaqui,Idália Maria Brasil; Dornelas,Conceição Aparecida; Escalante,Rodrigo Dornenfeld; Mota,Daniel Magalhães CoutinhoPURPOSE: Test immersion of microscopy samples in water as an aid to visualizing and quantifying aberrant crypt foci (ACF) in rat colon mucosa. METHODS: Carcinogenesis was induced with azoxymethane in Wistar rats kept on a conventional diet or a hypercaloric diet containing unsaturated fat. Fifteen weeks after induction, colon samples were retrieved and fixated in a 10% formaldehyde solution. The samples were di...