1 document found, page 1 of 1

Sort by Issue Date
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, M...

Houy, Sébastien; Groffen, Alexander J; Ziomkiewicz, Iwona; Verhage, Matthijs; Pinheiro, Paulo S.; Sørensen, Jakob Balslev

Doc2B is a cytosolic protein with binding sites for Munc13 and Tctex-1 (dynein light chain), and two C2-domains that bind to phospholipids, Ca2+ and SNAREs. Whether Doc2B functions as a calcium sensor akin to synaptotagmins, or in other calcium-independent or calcium-dependent capacities is debated. We here show by mutation and overexpression that Doc2B plays distinct roles in two sequential priming steps in mo...

Date: 2017   |   Origin: Estudo Geral - Universidade de Coimbra
More info.
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

1 Results

Queried text

Refine Results

Author







Date


Document Type


Access rights


Resource


Subject