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Finerenone, Obesity, and Heart Failure With Mildly Reduced/Preserved Ejection F...
Butt, Jawad H.; Henderson, Alasdair D.; Jhund, Pardeep S.; Claggett, Brian L.; Desai, Akshay S.; Lay-Flurrie, James; Viswanathan, PrabhakarPublisher Copyright: © 2025 The Authors; Background: Obesity is associated with excessive adipocyte-derived aldosterone secretion, independent of the classical renin-angiotensin-aldosterone cascade, and mineralocorticoid receptor antagonists may be more effective in patients with heart failure (HF) and obesity. Objectives: This study sought to examine the effects of the nonsteroidal mineralocorticoid receptor a...
Baseline characteristics of patients with heart failure with mildly reduced or ...
Solomon, Scott D.; Ostrominski, John W.; Vaduganathan, Muthiah; Claggett, Brian; Jhund, Pardeep S.; Desai, Akshay S.; Lam, Carolyn S.P.; Pitt, BertramPublisher Copyright: © 2024 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.; Aims: To describe the baseline characteristics of participants in the FINEARTS-HF trial, contextualized with prior trials including patients with heart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF). The FINEARTS-HF trial is ...