9 documents found, page 1 of 1
Experimental Trypanosoma cruzi infection induces pain in mice dependent on earl...
Verri, Waldiceu A.
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation...
Lemos, Henrique Paula; Grespan, Renata; Manfredo Vieira, Silvio; Cunha, Thiago Mattar; Verri, Waldiceu A.; Fernandes, Karla S.; Souto, Fabrício OliveiraIL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure. Here we report that prostaglandin enhances the IL-23/IL-17-induced neutrophil migration in a murine model of RA by inhibiting IL-12 and IFN γ production. Methylated BSA (mBSA) and IL-23-induced neutrophil migration was inhibited by anti-IL-23 and anti-IL-...
Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the developm...
Manfredo Vieira, Silvio; Cunha, Thiago Mattar; França, Rafael Freitas de Oliveira; Pinto, Larissa Garcia; Talbot, Jhimmy; Turato, Walter MiguelIntracellular pattern recognition receptors such as the nucleotide-binding oligomerization domain (NOD)-like receptors family members are key for innate immune recognition of microbial infection and may play important roles in the development of inflammatory diseases, including rheumatic diseases. In this study, we evaluated the role of NOD1 and NOD2 on development of experimental arthritis. Ag-induced arthriti...
Interleukin-33 receptor (ST2) deficiency improves the outcome of staphylococcus...
Verri, Waldiceu A.
The citrus flavanone naringenin reduces gout-induced joint pain and inflammatio...
Verri, Waldiceu A.
15d-PGJ(2)-loaded nanocapsules ameliorate experimental gout arthritis by reduci...
Ruiz-Miyazawa, Kenji W.; Staurengo-Ferrari, Larissa; Pinho-Ribeiro, Felipe A.; Fattori, Victor; Zaninelli, Tiago H.; Badaro-Garcia, StephanieMade available in DSpace on 2018-11-26T17:55:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-18; Pesquisa para o Sistema Unico de Saude (PPSUS) grant from Departamento de Ciencia e Tecnologia da Secretaria de Ciencia, Tecnologia e Insumos Estrategicos, Ministerio da Saude (Decit/SCTIE/MS, Brazil); Fundacao Araucaria and Secretaria Estadual de Saude, Parana (SESA-PR, Brazil); Fundação de Amparo à Pe...
Propolis reduces Leishmania amazonensis-induced inflammation in the liver of BA...
da Silva, Suelen S.; Mizokami, Sandra S.; Fanti, Jacqueline R.; Miranda, Milena M.; Kawakami, Natalia Y.; Teixeira, Fernanda HumelMade available in DSpace on 2018-12-11T16:59:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-04-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Experimental models of mouse paw infection with L. amazonensis show an induction of a strong inflammatory response in the skin, and parasitic migration may occur to ...
Targeting IL-33/ST2 signaling: regulation of immune function and analgesia
Verri, Waldiceu A.
Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflam...
Verri, Waldiceu A.