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Food safety assessment of an antifungal protein from Moringa oleifera seeds in ...

Pinto, Clidia E. M.; Farias, Davi F.; Carvalho, Ana F. U; Oliveira, Jose T. A.; Pereira, Mirella L.; Grangeiro, Thalles B.; Freire, Jose E. C.

Mo-CBP3 is an antifungal protein produced by Moringa oleifera which has been investigated as potential candidate for developing transgenic crops. Before the use of novel proteins, food safety tests must be conducted. This work represents an early food safety assessment of Mo-CBP3, using the two-tiered approach proposed by ILSI. The history of safe use, mode of action and results for amino acid sequence homology...

Date: 2021   |   Origin: Oasisbr

Gingerol fraction from zingiber officinale nephrotoxicity protects against gent...

Rodrigues, Francisco A. P.; Prata, Mara M. G.; Oliveira, Iris Cristina Maia; Alves, Natacha Teresa Queiroz; Freitas, Rosa E. M.; Monteiro, Helena S. A.

Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction of reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to have antioxidant and anti-inflammatory effects. We investigated if oral treatment with an enriched solution of gingerols (GF) would promote a nephroprotect...

Date: 2014   |   Origin: Oasisbr

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