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Estudo retrospectivo: doenças autoimunes do hospital veterinário da Universidad...

Macias, Loren; Massitel, Isabela; Viana, Danilo; De Albuquerque, Ana Paula; Taffarel, Marilda

Date: 2017   |   Origin: Oasisbr

Identification of hereditary cancer in the general population: development and ...

Campacci, Natália; Lima, Juliana O. de; Carvalho, André Lopes; Michelli, Rodrigo A. D.; Haikel Junior, Raphael L.; Mauad, Edmundo; Viana, Danilo

One of the challenges for Latin American countries is to include in their healthcare systems technologies that can be applied to hereditary cancer detection and management. The aim of the study is to create and validate a questionnaire to identify individuals with possible risk for hereditary cancer predisposition syndromes (HCPS), using different strategies in a Cancer Prevention Service in Brazil. The primary...


Optimization of a pentaplex panel for MSI analysis without control DNA in a Bra...

Campanella, Nathália C.; Berardinelli, Gustavo N.; Scapulatempo-Neto, Cristovam; Viana, Danilo; Palmero, Edenir I.; Pereira, Rui; Reis, R. M.

Microsatellite instability (MSI) testing has been advocated for all newly diagnosed colorectal cancer patients. One of the most common tests is composed by a pentaplex panel of mononucleotides markers (NR-27, NR-21, NR-24, BAT-25, and BAT-26), which allows the analysis of MSI in tumors without the need of reference DNA. For that, it is fundamental to establish a quasi-monomorphic variation range (QMVR) for each...


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