Multiple Myeloma (MM) is a hematological neoplasm characterized by bone marrow infiltration by clonal (malignant) plasma cells and the production of a monoclonal protein (MP). The disease remains incurable, although in recent years, with the advent of new treatments, progressive improvements in rates and duration of remission have been observed, resulting in a significant survival increment for affected patient...
The two-hit model proposes that genetic or behavioral challenges in periods considered critical in neurodevelopment, as early in life and during the transition from childhood to adolescence, can affect the normal development of the brain and predispose the individual to psychopathology. These events can occur differently between genders. The objective of this study was to investigate the behavioral and neuroche...