13 documents found, page 1 of 2
Acute kidney injury associated with COVID-19 infection: a case report
Duarte,Tiago; Caeiro,Fernando; Góis,Mário; Matos,António; Viana,Helena; Vieira,César; Paulos,Jorge; Paixão,Paulo; Matos,Bruno; Germano,NunoABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tu...
Nephrotic syndrome in a patient with metastatic melanoma: beyond the obvious
Messias,Ana; Calado,Joaquim; Viana,Helena; Nolasco,FernandoNephrotic syndrome in a patient with metastatic melanoma can occur in the context of a paraneoplastic glomerulopathy or as a complication of treatment. New oncologic immunotherapies, including immune checkpoint inhibitors, have been frequently associated with interstitial nephritis and, in rare cases, with nephrotic syndrome. This article presents the case of a 52-year-old man diagnosed with metastatic melanoma...
Rivaroxaban-related nephropathy
Oliveira,Miguel; Lima,Carla; Góis,Mário; Viana,Helena; Carvalho,Fernanda; Lemos,SérgioNovel oral anticoagulants (NOAC) are a group of drugs recently approved for the treatment of patients at high risk of arterial or venous thrombosis. Unlike vitamin K antagonists, NOAC have a faster onset of action, less drug interactions and do not need frequent monitoring, making their prescription more convenient for physicians and patients. However, both classes of drugs have the potential for nephrotoxicity...
A rare malignancy in the post-transplant period: Myeloma cast nephropathy
Mesquita,Isabel; Viana,Helena; Possante,Marília; João,Cristina; Carvalho,Susana; Silva,Cecília; Aires,Inês; Ferreira,Aníbal; Remédio,FranciscoMyeloma-associated renal disorders are rare events among renal transplants and can occur as recurrent or de novo disease. We describe an unusual case of renal allograft dysfunction due to myeloma cast nephropathy occurring 19 years after having received a renal transplant in a patient with no prior history of multiple myeloma or monoclonal gammopathy preceding transplantation. Our patient was treated with five ...
In-centre nocturnal haemodialysis: The experience of a centre
Mesquita,Isabel; Lobos,Ana Vila; Viana,Helena; Lopes,João; Costa,Teixeira e; Resina,Cristina; Guerra,Alexandra; Ramos,Aura; Remedio,FranciscoBackground and Objectives: As a result of improved clinical and quality-of-life outcomes, in-centre nocturnal haemodialysis emerges as one of the alternatives to conventional haemodialysis. Even today, little is known about the flow of patients through in-centre nocturnal haemodialysis programmes or about patients survival or technique failure. This study sought to address this gap in knowledge. Materials and ...
Anti-phospholipase A2 receptor antibodies in the diagnosis of idiopathic membra...
Meneses,Guida; Viana,Helena; Santos,Maria C.; Ferreira,Carina; Calado,Joaquim; Carvalho,Fernanda; Remedio,Francisco; Nolasco,FernandoCirculating anti-phospholipase A2 receptor antibodies (anti-PLA2R) have been described in 70% to 80% of the patients with idiopathic membranous nephropathy (iMN), but not in patients with secondary membranous nephropathy or other glomerular diseases. The goal of this study was to evaluate the sensitivity and specificity of the assay for anti-PLA2R in the diagnosis of iMN. Anti-PLA2R IgG, Elisa and immunofluores...
Idiopathic hypocomplementaemic tubulointerstitial nephritis
Azevedo,Ana; Mesquita,Isabel; Viana,Helena; Rocha,Gizela; Ferreira,Carina; Fernandes,Vasco; Murinello,Antonio; Carvalho,Fernanda; Nolasco,FernandoBackground: Tubulointerstitial nephritis (TIN) is a common cause of kidney injury typically seen in association with drug exposure, infection or autoimmune diseases. However, TIN with interstitial immune complex deposition, without glomerular injury, is rarely observed. Case: We report a case of a 64-yearold Indian woman admitted for dialysis-requiring renal failure, without involvement of other organs. Urinaly...
Henoch-Schönlein purpura associated with pulmonary adenocarcinoma
Azevedo,Ariana; Fernandes,Vasco; Navarro,David; Ferreira,Ana Carina; Sousa,João; Viana,Helena; Carvalho,Fernanda; Nolasco,FernandoIntroduction: The Henoch-Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated smallvessel systemic vasculitis, rare in adults. The association with solid tumours has been described, especially with lung cancer. Case Report: We present the case of a 60-year-old Caucasian male, diag- nosed with lung adenocarcinoma that underwent surgical resection without (neo)adjuvant theraphy. Two months latter he was ...
Early renal protocol biopsies: for some but not for all renal transplant patients?
Navarro,David; Ferreira,Ana Carina; Caeiro,Fernando; Cotovio,Patricia; Aires,Ines; Silva,Cecilia; Remedio,Francisco; Ferreira,Anibal; Viana,HelenaSubclinical rejection following renal transplant is associated with worse outcomes, which can be prevented if recognized early. Protocol allograft biopsies have emerged as an option to identify and allow treatment of subclinical rejection, but optimal timing for their performance is not established. We retrospectively evaluated a cohort of 52 low immunological risk patients, who were submitted, from 2007 to 201...
Renal Disease in Madeira Islands: twenty-seven years' experience of native kidn...
Vieira,Pedro; Goncalves,Antonio M; Duraes,Jose M; Rosa,Nuno G; Resende,Luis; Silva,Gil; Teixeira,Alves; Rodrigues,Fernando; Galvão,Maria J; Brinca,AnaIntroduction: Renal biopsy plays an essential role either in the diagnosis or in the prognosis of patients with renal disease. In order to assess its epidemiology and evolution in Madeira Islands, we analysed twenty-seven years of native kidney biopsies. Methods: We performed a retrospective analysis of clinical records, including histological revision from 1986 to 2012, totalling 315 native kidney biopsies. Th...