8 documents found, page 1 of 1
Potencial de integração de energia solar térmica de concentração em processos d...
Loureiro, David; Miranda, Miguel; Martins, António; Viegas, Sandra; Rodrigues, Hugo; Lobo, Gonzalo; Prieto, Elisabet Gonzalez; Galan, Silvia PérezRESUMO: A consciencialização dos problemas resultantes das atividades económicas relacionadas com a gestão de resíduos nas regiões transfronteiriças da Andaluzia-Algarve-Alentejo (AAA), conduziu ao desenvolvimento do projeto SECASOL. Este projeto de cooperação visa a integração de energia solar térmica de concentração (ESTC) nos processos de secagem de lamas de depuração de águas residuais (ETAR) e de resíduos ...
Potencial de integração de energia solar térmica de concentração em processos d...
Loureiro, David; Miranda, Miguel; Martins, António; Viegas, Sandra; Rodrigues, Hugo; Lobo, Gonzalo; Prieto, Elisabet Gonzalez; Galan, Silvia PérezRESUMO: A consciencialização dos problemas resultantes das atividades económicas relacionadas com a gestão de resíduos nas regiões transfronteiriças da Andaluzia-Algarve-Alentejo (AAA), conduziu ao desenvolvimento do projeto SECASOL. Este projeto de cooperação visa a integração de energia solar térmica de concentração (ESTC) nos processos de secagem de lamas de depuração de águas residuais (ETAR) e de resíduos ...
The Ady2 “NPAPLGL(M/S)” motif is critical for acetate uptake and binding
Ribas, David Manuel Nogueira; Soares-Silva, Isabel João; Vieira, Daniel; Sousa-Silva, M.; Sá-Pessoa, Joana; Silva, João Pedro Azevedo; Viegas, SandraOrganic acids, such as acetate, are recognized as one of the most prevalent compounds in ecosystems and the transport, biosynthesis, and assimilation of these molecules represent an adaptive advantage for organisms. The majority of AceTr family members so far characterized were associated with the active transport of acetate. AceTr proteins have six predicted transmembrane segments (TMS), sharing the conserved ...
An unexpected role for DIS3L2 over human NMD targets
Costa, Paulo; Saramago, Margarida; Viegas, Sandra; Arraiano, Cecília; Romão, LuísaThe nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs carrying a premature translation-termination codon but also regulates the abundance of a large number of physiological RNAs that encode full-length proteins. In human cells, NMD-targeted mRNAs are degraded by endonucleolytic cleavage and exonucleolytic degradation from both 5’ and 3’ ends. This is done by a process not yet completely unde...
Behind the curtain: unveiling DIS3L2 role in NMD and human cancer
Costa, Paulo; Saramago, Margarida; Viegas, Sandra; Arraiano, Cecília; Romão, LuísaNonsense-mediated mRNA decay (NMD) is a surveillance mechanism that targets and degrades mRNAs carrying premature translation-termination codons (PTCs), preventing the production of truncated proteins potentially harmful for the cells. In addition to this, several studies have shown that NMD regulates the levels of many physiological mRNAs that encode full-length proteins. Nevertheless, NMD is inhibited in tumo...
An unexpected role for DIS3L2 over human NMD targets
Costa, Paulo; Saramago, Margarida; Viegas, Sandra; Arraiano, Cecília; Santos, Hugo; Gama-Carvalho, Margarida; Romão, LuísaThe final step of cytoplasmic mRNA degradation proceeds in either a 5’-3’ direction, catalyzed by XRN1, or in a 3’-5’ direction catalyzed by the exosome and DIS3L2. In yeast, DIS3/Rrp44 protein is the catalytic subunit of the exosome. In humans, there are three known paralogues of this enzyme: DIS3, DIS3L1, and DIS3L2. Important findings over the last years have shed a new light onto the mechanistic details of ...
Comparison of discriminant analysis methods: Application to occupational exposu...
Ramos, Maria do Rosário; Carolino, E.; Viegas, Carla; Viegas, SandraHealth effects associated with occupational exposure to particulate matter have been studied by several authors. In this study were selected six industries of five different areas: Cork company 1, Cork company 2, poultry, slaughterhouse for cattle, riding arena and production of animal feed. The measurements tool was a portable device for direct reading. This tool provides information on the particle number con...
Discovery and initial characterization of members of the new YaaH family of mic...
Pessoa, Joana Sá; Viegas, Sandra; Rocha, Gabriel Azevedo Carreira Talaia da; Diallinas, George; Paiva, Sandra; Arraiano, Cecilia; Casal, MargaridaThe emergence of probiotics and prebiotics has revived the importance of short-chain fatty acids (SCFAs) associated to colonic and systemic health improvement. Although biosynthesis and degradation of SCFAs and other short-chain carboxylic acids, such as lactate, pyruvate or citrate are well understood, the transport of these acids is still a matter of discussion. The presence of SCFAs transporters in cellular ...