2 documents found, page 1 of 1
Renal tubular dysfunction in sickle cell disease
Silva Junior, Geraldo B.; Vieira, Ana Patrícia F.; Bem, Amanda X. Couto; Alves, Marília P.; Meneses, Gdayllon C.; Martins, Alice M.C.Background/Aims: Kidney abnormalities are one of the main chronic complications of sickle cell disease (SCD). The aim of this study is to investigate the occurrence of renal tubular abnormalities among patients with SCD. Methods: This is a prospective study with 26 SCD adult patients in Brazil. Urinary acidification and concentration tests were performed using calcium chloride (CaCl2), after a 12h period of wat...
Factors associated with thrombocytopenia in severe leptospirosis (Weil’s disease)
Daher, Elizabeth de Francesco; Silva Junior, Geraldo B.; Silveira, Charles O.; Falcão, Felipe S.; Alves, Marília P.; Mota, Jório A. A. A.OBJECTIVE: This study was conducted to investigate factors associated with thrombocytopenia in a large cohort of patients with leptospirosis in an endemic area. METHODS: This retrospective study included 374 consecutive patients with leptospirosis who were admitted to tertiary hospitals in Fortaleza, Brazil. All patients had a diagnosis of severe leptospirosis (Weil’s disease). Acute kidney injury was defined a...