Paraquat (PQ) is a toxic quaternary ammonium compound widely used in agriculture. Numerous cases of paraquat intoxication have been reported either accidentally or intentionally as suicidal attempts. A method for the determination of the herbicide PQ in blood and urine samples was developed using liquid chromatography-(electrospray ionization) mass spectrometry (LCESI-MS), following extraction with Oasis® WCX s...
The tooth is an important sample in adverse forensic conditions. Its morphology and histology contributes for the preservation of the cellular components.; http://www.sciencedirect.com/science/article/B8JHP-4SBRTWX-V/1/4edd71a84d252ef01f799c324b50a993
The main objective of this paper is to show that, despite some adverse forensic condition such as degraded human body remains and exhumed material, the dentine (in pulp dentine complex) keeps, in the majority of cases, its integrity. In this study, we use a sample of 30 human teeth (both with and without carious) after extraction during dental treatment. We analyze 15 STRs and both high-variable regions I and I...
In this study we continue the genetic characterization of human populations from East Timor, as previously started for autosomal STRs and Y STRs, with a preliminary report on mitochondrial DNA (mtDNA) diversity. Individual samples (n = 133) collected from all the districts of East Timor and representing different linguistic groups were studied for the hypervariable region 1 (HVS1) sequence and the 9-bp deletion...
Haplotype frequencies were determined for 346 individuals from East Timor and 3 major ethnolinguistic groups were compared, putting in evidence the need for detailed analyses below the level of the major ethnolinguistic groups. Search of Timorese haplotypes matches in international databases returns few hits and almost all with Philippine data.; http://www.sciencedirect.com/science/article/B7581-4JSBXBX-37/1/9d...
http://www.sciencedirect.com/science/article/B6T6W-4FVJC03-2/1/4d12524a22b2805e723ce2af692237f6
Allele frequencies for the fifteen STRs included in the AmpF/STR Identifiler (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPO and VWA) were estimated from a sample of 186 unrelated individuals from East Timor. No deviations from Hardy-Weinberg equilibrium were observed (only after applying the Bonferroni correction in the cases of D2S1338, TPO and D5S...
The study of the Y-chromosome is very important for forensic and population genetics. Although many populations have already been analysed, there is little data about Brazilian populations. The haplotype frequency of eight Y-STRs: DYS437, DYS438, DYS439, DYS460 (Y-GATA-A7.1), DYS461 (Y-GATA-A7.2), Y-GATA-A10, Y-GATA-C4 and Y-GATA-H4 in 72 male individuals from Bahia was established. A total of 67 different hapl...
The first population-genetics study for the world newest independent country, East Timor, is presented. In this preliminary work, part of a major ongoing study on East-Timor genetic diversity, the allele frequencies and some statistical parameters of forensic interest were determined for the 15 loci included in AmpFLSTR Identifiler(TM) genotyping kit. A total of 107 samples, collected from East Timorese of seve...
Fenarimol (Rubigan®) is a pyrimidine ergosterol biosynthesis inhibitor used as a systemic fungicide. The authors present a fatal fenarimol intoxication case analysed in the Forensic Toxicology Service of the National Institute of Legal Medicine. The results were used to compare two different HPLC techniques, regarding selectivity and sensitivity: an HPLC system with a diode array detector (DAD) and an HPLC syst...