2 documents found, page 1 of 1
Co-expression network of neural-differentiation genes shows specific pattern in...
Maschietto, Mariana; Tahira, Ana C.; Puga, Renato; Lima, Leandro; Mariani, Daniel; Paulsen, Bruna da Silveira; Belmonte-de-Abreu, PauloBackground: Schizophrenia is a neurodevelopmental disorder with genetic and environmental factors contributing to its pathogenesis, although the mechanism is unknown due to the difficulties in accessing diseased tissue during human neurodevelopment. The aim of this study was to find neuronal differentiation genes disrupted in schizophrenia and to evaluate those genes in post-mortem brain tissues from schizophre...
Digoxin in advanced heart failure patients: a question of rhythm
Jorge, Elisabete; Baptista, Rui; Martins, Hélia; Saraiva, Fátima; Costa, Susana; Vieira, Henrique; Coelho, Lourenço; Monteiro, Pedro; Franco, FátimaBackground: The impact of digoxin on outcomes of patients with advanced heart failure (HF) remains uncertain and its effect may be different for patients in atrial fibrillation (AF) or sinus rhythm (SR). Objectives: To determine the impact of digoxin on outcomes of advanced HF patients and to assess whether prognosis differs in patients in AF and SR. Methods: A total of 268 consecutive patients admitted to an i...